Is there a link between infections and asthma?

被引:0
作者
Indolfi, C. [1 ]
Klain, A. [1 ]
Di Nardo, G. [2 ]
Cuppari, C. [3 ]
Ceravolo, A.
Concolino, D. [4 ]
De Sarro, R. [5 ]
Salpietro, A. [6 ]
Decimo, F. [1 ]
del Giudice, M. Miraglia [1 ]
机构
[1] Univ Campania Luigi Vanvitelli, Dept Woman Child & Specialized Surg, Naples, Italy
[2] Univ Hosp G Martino, Dept Human Pathol Adult & Childhood G Barresi, Neonatal & Pediat Intens Care Unit, Messina, Italy
[3] Univ Messina, Dept Human Pathol Adult & Dev Age Gaetano Barresi, Unit Emergency Pediat, G Martino Policlin, Messina, Italy
[4] Magna Graecia Univ Catanzaro, Dept Hlth Sci, Pediat Unit, Catanzaro, Italy
[5] Univ Hosp Messina, Dept Clin & Expt Med, Messina, Italy
[6] ASST Spedali Civili Brescia, Pediat Clin, Brescia, Italy
关键词
infections; asthma; children; RESPIRATORY SYNCYTIAL VIRUS; VIRAL-INFECTIONS; RHINOVIRUS INFECTION; PALIVIZUMAB PROPHYLAXIS; ALLERGIC SENSITIZATION; BACTERIAL-COLONIZATION; ACUTE EXACERBATIONS; CHILDHOOD ASTHMA; DISEASE SEVERITY; UNITED-STATES;
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Asthma is a common chronic condition affecting both children and adults and is characterized by chronic airway inflammation leading to bronchial hyperresponsiveness and mucous hypersecretion. Asthma can be triggered by various stimuli, leading to recurrent and reversible episodes of wheezing, shortness of breath, chest tightness, and coughing (1). Globally, about 235 million people suffer from asthma. Implicated in the development of asthma are respiratory viral infections and infections with atypical bacteria (such as mycoplasma and/or chlamydia) (2). The burden of asthma is significant, both in terms of financial expenses and lost productivity, and in many situations, it is an infectious agent that initiates an asthma exacerbation. This review will discuss the strong link between asthma and infections and the potential mechanisms to translate these infections into asthma.
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收藏
页码:159 / 169
页数:11
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