The CpG island methylator phenotype in colorectal cancer

被引:37
作者
Samowitz, Wade S. [1 ]
机构
[1] Univ Utah, Hlth Sci Ctr, Dept Anat Pathol, Salt Lake City, UT 84132 USA
关键词
D O I
10.2353/jmoldx.2007.070031
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
引用
收藏
页码:281 / 283
页数:3
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共 19 条
[1]   BRAF mutation is frequently present in sporadic colorectal cancer with methylated hMLH1, but not in hereditary nonpolyposis colorectal cancer [J].
Deng, GR ;
Bell, I ;
Crawley, S ;
Gum, J ;
Terdiman, JP ;
Allen, BA ;
Truta, B ;
Sleisenger, MH ;
Kim, YS .
CLINICAL CANCER RESEARCH, 2004, 10 (01) :191-195
[2]   BRAF screening as a low-cost effective strategy for simplifying HNPCC genetic testing [J].
Domingo, E ;
Laiho, P ;
Ollikainen, M ;
Pinto, M ;
Wang, L ;
French, AJ ;
Westra, J ;
Frebourg, T ;
Espín, E ;
Armengol, M ;
Hamelin, R ;
Yamamoto, H ;
Hofstra, RMW ;
Seruca, R ;
Lindblom, A ;
Peltomäki, P ;
Thibodeau, SN ;
Aaltonen, LA ;
Schwartz, S .
JOURNAL OF MEDICAL GENETICS, 2004, 41 (09) :664-668
[3]   CpG island methylation in sporadic colorectal cancers and its relationship to microsatellite instability [J].
Hawkins, N ;
Norrie, M ;
Cheong, K ;
Mokany, E ;
Ku, SL ;
Meagher, A ;
O'Connor, T ;
Ward, R .
GASTROENTEROLOGY, 2002, 122 (05) :1376-1387
[4]   Methylation-specific PCR: A novel PCR assay for methylation status of CpG islands [J].
Herman, JG ;
Graff, JR ;
Myohanen, S ;
Nelkin, BD ;
Baylin, SB .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (18) :9821-9826
[5]   CIMP, at last [J].
Issa, JPJ ;
Shen, LL ;
Toyota, M .
GASTROENTEROLOGY, 2005, 129 (03) :1121-1124
[6]   BRAF mutation is associated with DNA methylation in serrated polyps and cancers of the colorectum [J].
Kambara, T ;
Simms, LA ;
Whitehall, VLJ ;
Spring, KJ ;
Wynter, CVA ;
Walsh, MD ;
Barker, MA ;
Arnold, S ;
McGivern, A ;
Matsubara, N ;
Tanaka, N ;
Higuchi, T ;
Young, J ;
Jass, JR ;
Leggett, BA .
GUT, 2004, 53 (08) :1137-1144
[7]  
McGivern A, 2004, Fam Cancer, V3, P101
[8]   Colorectal cancer with mutation in BRAF, KRAS, and wild-type with respect to both oncogenes showing different patterns of DNA methylation [J].
Nagasaka, T ;
Sasamoto, H ;
Notohara, K ;
Cullings, HM ;
Takeda, M ;
Kimura, K ;
Kambara, T ;
MacPhee, DG ;
Young, J ;
Leggett, BA ;
Jass, JR ;
Tanaka, N ;
Matsubara, N .
JOURNAL OF CLINICAL ONCOLOGY, 2004, 22 (22) :4584-4594
[9]   Evaluation of markers for CpG island methylator phenotype (CIMP) in colorectal cancer by a large population-based sample [J].
Ogino, Shuji ;
Kawasaki, Takako ;
Kirkner, Gregory J. ;
Kraft, Peter ;
Loda, Massimo ;
Fuchs, Charles S. .
JOURNAL OF MOLECULAR DIAGNOSTICS, 2007, 9 (03) :305-314
[10]   CpG island methylator phenotype-low (CIMP-Low) in colorectal cancer:: Possible associations with male sex and KRAS mutations [J].
Ogino, Shuji ;
Kawasaki, Takako ;
Kirkner, Gregory J. ;
Loda, Massimo ;
Fuchs, Charles S. .
JOURNAL OF MOLECULAR DIAGNOSTICS, 2006, 8 (05) :582-588