Cryptosporidium species:: New insights and old challenges

被引：59

作者：

Leav, BA ^{[1
]}

Mackay, M ^{[1
]}

Ward, HD ^{[1
]}

机构：

[1] Tufts New England Med Ctr, Div Geog Med & Infect Dis, Boston, MA 02111 USA

来源：

CLINICAL INFECTIOUS DISEASES | 2003年 / 36卷 / 07期

关键词：

D O I：

10.1086/368194

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Cryptosporidium species are protozoan parasites that cause mainly enteric illnesses in humans and other animals. The mode of transmission is most commonly waterborne, but other sources of infection, including foodborne and person-to-person spread, have been documented. The environmental form of the parasite is resistant to most water purification methods, including chlorination. Cryptosporidium infection usually causes a self-limited diarrheal illness but can be life-threatening in immunocompromised individuals. There is no effective therapy for cryptosporidiosis.

引用

页码：903 / 908

页数：6

共 31 条

[11] TIMING OF SYMPTOMS AND OOCYST EXCRETION IN HUMAN CRYPTOSPORIDIOSIS [J].

JOKIPII, L ;

JOKIPII, AMM .

NEW ENGLAND JOURNAL OF MEDICINE, 1986, 315 (26) :1643-1647

[12] The role of cytokines in the pathogenesis of Cryptosporidium infection [J].

Lean, IS ;

McDonald, V ;

Pollok, RCG .

CURRENT OPINION IN INFECTIOUS DISEASES, 2002, 15 (03) :229-234

[13] Analysis of sequence diversity at the highly polymorphic Cpgp40/15 locus among Cryptosporidium isolates from human immunodeficiency virus-infected children in South Africa [J].

Leav, BA ;

Mackay, MR ;

Anyanwu, A ;

O'Connor, RM ;

Cevallos, AM ;

Kindra, G ;

Rollins, NC ;

Bennish, ML ;

Nelson, RG ;

Ward, HD .

INFECTION AND IMMUNITY, 2002, 70 (07) :3881-3890

[14] Persistent diarrhea signals a critical period of increased diarrhea burdens and nutritional shortfalls: A prospective cohort study among children in northeastern Brazil [J].

Lima, AAM ;

Moore, SR ;

Barboza, MS ;

Soares, AM ;

Schleupner, MA ;

Newman, RD ;

Sears, CL ;

Nataro, JP ;

Fedorko, DP ;

Wuhib, T ;

Schorling, JB ;

Guerrant, RL .

JOURNAL OF INFECTIOUS DISEASES, 2000, 181 (05) :1643-1651

[15] A clinicopathologic analysis of AIDS-related cryptosporidiosis [J].

Lumadue, JA ;

Manabe, YC ;

Moore, RD ;

Belitsos, PC ;

Sears, CL ;

Clark, DP .

AIDS, 1998, 12 (18) :2459-2466

[16] MASSIVE OUTBREAK OF WATERBORNE CRYPTOSPORIDIUM INFECTION IN MILWAUKEE, WISCONSIN - RECURRENCE OF ILLNESS AND RISK OF SECONDARY TRANSMISSION [J].

MACKENZIE, WR ;

SCHELL, WL ;

BLAIR, KA ;

ADDISS, DG ;

PETERSON, DE ;

HOXIE, NJ ;

KAZMIERCZAK, JJ ;

DAVIS, JP .

CLINICAL INFECTIOUS DISEASES, 1995, 21 (01) :57-62

[17] Cryptosporidiosis in patients with AIDS: Correlates of disease and survival [J].

Manabe, YC ;

Clark, DP ;

Moore, RD ;

Lumadue, JA ;

Dahlman, HR ;

Belitsos, PC ;

Chaisson, RE ;

Sears, CL .

CLINICAL INFECTIOUS DISEASES, 1998, 27 (03) :536-542

[18] Variation in Cryptosporidium:: towards a taxonomic revision of the genus [J].

Morgan, UM ;

Xiao, LH ;

Fayer, R ;

Lal, AA ;

Thompson, RCA .

INTERNATIONAL JOURNAL FOR PARASITOLOGY, 1999, 29 (11) :1733-1751

[19]

NIME FA, 1976, GASTROENTEROLOGY, V70, P592

[20] Genetic polymorphism among Cryptosporidium parvum isolates: Evidence of two distinct human transmission cycles [J].

Peng, MM ;

Xiao, LH ;

Freeman, AR ;

Arrowood, MJ ;

Escalante, AA ;

Weltman, AC ;

Ong, CSL ;

MacKenzie, WR ;

Lal, AA ;

Beard, CB .

EMERGING INFECTIOUS DISEASES, 1997, 3 (04) :567-573

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