Aqueous Phase Synthesis of Highly Luminescent, Nitrogen-Doped Carbon Dots and Their Application as Bioimaging Agents

被引：110

作者：

Wang, Li ^{[1
]}

Yin, Yuan ^{[2
]}

Jain, Anjana ^{[2
]}

Zhou, H. Susan ^{[1
]}

机构：

[1] Worcester Polytech Inst, Life Sci & Bioengn Ctr, Dept Chem Engn, Worcester, MA 01609 USA

[2] Worcester Polytech Inst, Life Sci & Bioengn Ctr, Dept Biomed Engn, Worcester, MA 01609 USA

来源：

LANGMUIR | 2014年 / 30卷 / 47期

基金：

美国国家科学基金会;

关键词：

HIGH QUANTUM YIELD; FACILE SYNTHESIS; OPTICAL-PROPERTIES; FLUORESCENT-PROBE; BRAIN-TUMORS; NANOPARTICLES; NANODOTS; IONS; PHOTOLUMINESCENCE; THERAPY;

D O I：

10.1021/la5031813

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Carbon dots are promising scaffolds for multifunctional therapeutic systems because of their fluorescence property, good biocompatibility, and low toxicity. In this work, we prepared nitrogen-doped carbon dots through an aqueous phase strategy using folic acid as precursor. The carbon dots possess many attractive features including uniform dispersion with size about 9 nm, bright photoluminescence, high photoluminescence quantum yield of 23%, and low toxicity, making them excellent imaging probes for biomedical applications.

引用

页码：14270 / 14275

页数：6

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