Biomimetic Total Synthesis of Rhodonoids C and D, and Murrayakonine D

被引：21

作者：

Day, Aaron J. ^{[1
]}

Lamr, Hiu C. ^{[1
]}

Sumby, Christopher J. ^{[1
]}

George, Jonathan H. ^{[1
]}

机构：

[1] Univ Adelaide, Dept Chem, Adelaide, SA 5005, Australia

来源：

ORGANIC LETTERS | 2017年 / 19卷 / 10期

基金：

澳大利亚研究理事会;

关键词：

RHODODENDRON-CAPITATUM; CARBAZOLE ALKALOIDS; RING-CLOSURE; (-)-SICCANIN; CYCLIZATIONS; RULES; PAIRS;

D O I：

10.1021/acs.orglett.7b00779

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A divergent, three-step total synthesis of rhodonoids C and D has been achieved using a biosynthetically inspired, acid-catalyzed cascade cyclization of an epoxychromene that involves the presumed intermediacy of o-quinone methides. Application of a similar strategy also allowed synthesis of the alkaloid murrayakonine D.

引用

页码：2463 / 2465

页数：3

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