Acquired slow-channel syndrome

被引：0

作者：

Scola, RH ^{[1
]}

Werneck, LC ^{[1
]}

Iwamoto, FM ^{[1
]}

Comerlato, EA ^{[1
]}

Kay, CK ^{[1
]}

机构：

[1] Univ Fed Parana, Hosp Clin, Neuromuscular Disorders Div, BR-80069900 Curitiba, Parana, Brazil

来源：

MUSCLE & NERVE | 2000年 / 23卷 / 10期

关键词：

electromyography; myasthenia gravis; neuromuscular junction; slow-channel syndrome;

D O I：

10.1002/1097-4598(200010)23:10<1582::AID-MUS16>3.3.CO;2-8

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We report the case of a 37-year-old man with clinical and electrophysiological features of hereditary slow-channel syndrome (SCS) and antibodies against acetylcholine receptors (AChR-Abs). He presented with weakness of shoulder and hand muscles. A supramaximal single stimulus to the motor nerves disclosed a double compound muscle action potential (CMAP). Repetitive stimulation of ulnar, suprascapular, and median nerves showed a CMAP decrement greater than 10%. The patient responded to pyridostigmine. This report confirms the importance of AChR-Ab titers in suspected cases of hereditary SCS because patients with positive AChR-Abs may have a better response to available treatments. (C) 2000 John Wiley & Sons, Inc.

引用

页码：1582 / 1585

页数：4

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