The University of Minnesota Biocatalysis/Biodegradation Database: improving public access

被引：243

作者：

Gao, Junfeng ^{[1
]}

Ellis, Lynda B. M. ^{[1
]}

Wackett, Lawrence P. ^{[2
]}

机构：

[1] Univ Minnesota, Dept Lab Med & Pathol, Minneapolis, MN 55455 USA

[2] Univ Minnesota, Dept Biochem Mol Biol & Biophys, St Paul, MN 55108 USA

来源：

NUCLEIC ACIDS RESEARCH | 2010年 / 38卷

基金：

美国国家科学基金会;

关键词：

INFORMATION-SYSTEM; TOOLS;

D O I：

10.1093/nar/gkp771

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The University of Minnesota Biocatalysis/Biodegradation Database (UM-BBD, http://umbbd.msi.umn.edu/) began in 1995 and now contains information on almost 1200 compounds, over 800 enzymes, almost 1300 reactions and almost 500 microorganism entries. Besides these data, it includes a Biochemical Periodic Table (UM-BPT) and a rule-based Pathway Prediction System (UM-PPS) (http://umbbd.msi.umn.edu/predict/) that predicts plausible pathways for microbial degradation of organic compounds. Currently, the UM-PPS contains 260 biotransformation rules derived from reactions found in the UM-BBD and scientific literature. Public access to UM-BBD data is increasing. UM-BBD compound data are now contributed to PubChem and ChemSpider, the public chemical databases. A new mirror website of the UM-BBD, UM-BPT and UM-PPS is being developed at ETH Zurich to improve speed and reliability of online access from anywhere in the world.

引用

页码：D488 / D491

页数：4

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