The University of Minnesota Biocatalysis/Biodegradation Database: improving public access

被引：236
作者：
Gao, Junfeng [1 ]
Ellis, Lynda B. M. [1 ]
Wackett, Lawrence P. [2 ]
机构：
[1] Univ Minnesota, Dept Lab Med & Pathol, Minneapolis, MN 55455 USA
[2] Univ Minnesota, Dept Biochem Mol Biol & Biophys, St Paul, MN 55108 USA
来源：
NUCLEIC ACIDS RESEARCH | 2010年 / 38卷
基金：
美国国家科学基金会;
关键词：
INFORMATION-SYSTEM; TOOLS;
D O I：
10.1093/nar/gkp771
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The University of Minnesota Biocatalysis/Biodegradation Database (UM-BBD, http://umbbd.msi.umn.edu/) began in 1995 and now contains information on almost 1200 compounds, over 800 enzymes, almost 1300 reactions and almost 500 microorganism entries. Besides these data, it includes a Biochemical Periodic Table (UM-BPT) and a rule-based Pathway Prediction System (UM-PPS) (http://umbbd.msi.umn.edu/predict/) that predicts plausible pathways for microbial degradation of organic compounds. Currently, the UM-PPS contains 260 biotransformation rules derived from reactions found in the UM-BBD and scientific literature. Public access to UM-BBD data is increasing. UM-BBD compound data are now contributed to PubChem and ChemSpider, the public chemical databases. A new mirror website of the UM-BBD, UM-BPT and UM-PPS is being developed at ETH Zurich to improve speed and reliability of online access from anywhere in the world.
引用
收藏
页码：D488 / D491
页数：4
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