Oxytocin Administration in Low-Risk Women, a Retrospective Analysis of Birth and Neonatal Outcomes

被引：12

作者：

Espada-Trespalacios, Xavier ^{[1
,2
,3
]}

Ojeda, Felipe ^{[1
]}

Perez-Botella, Mercedes ^{[4
,5
]}

Mila Villarroel, Raimon ^{[6
]}

Bach Martinez, Montserrat ^{[1
]}

Figuls Soler, Helena ^{[1
]}

Anquela Sanz, Israel ^{[6
]}

Rodriguez Coll, Pablo ^{[7
]}

Escuriet, Ramon ^{[3
,8
]}

机构：

[1] Hosp Gen Granollers, Dept Obstet & Gynecol, Avinguda Francesc Ribas S-N, Granollers 08402, Spain

[2] Univ Pompeu Fabra UPF, Dept Expt & Hlth Sci, Doctor Aiguader 88, Barcelona 08003, Spain

[3] Univ Ramon Llull, Res Grp Global Hlth Gender & Soc GHenderS, Carrer Padilla 326, Barcelona 08025, Spain

[4] Univ Cent Lancashire, Res Childbirth & Hlth Unit ReaRH, Preston PR1 2HE, Lancs, England

[5] Hosp Gen Granollers, Dept Neonatol, Avinguda Francesc Ribas S-N, Granollers 08402, Spain

[6] Univ Ramon Llull, Sch Hlth Sci Blanquerna, Carrer Padilla 326, Barcelona 08025, Spain

[7] Hosp Badalona Germans Trias & Pujol, Obstet Care Area, Carretera Canyet S-N, Badalona 08916, Spain

[8] Govt Catalonia, Catalan Hlth Serv, Travessera Corts 131, Barcelona 08028, Spain

来源：

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH | 2021年 / 18卷 / 08期

关键词：

term birth; obstetric labor; oxytocin; low-risk pregnancy; birth outcome; neonatal outcome; ELECTIVE-INDUCTION; SPONTANEOUS LABOR; EPIDURAL ANALGESIA; AUGMENTATION; EXPERIENCES; GUIDELINES; DELIVERY; DYSTOCIA; COHORT;

D O I：

10.3390/ijerph18084375

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Background: In recent years, higher than the recommended rate of oxytocin use has been observed among low-risk women. This study examines the relationship between oxytocin administration and birth outcomes in women and neonates. Methods: A retrospective analysis of birth and neonatal outcomes for women who received oxytocin versus those who did not. The sample included 322 women with a low-risk pregnancy. Results: Oxytocin administration was associated with cesarean section (aOR 4.81, 95% CI: 1.80-12.81), instrumental birth (aOR 3.34, 95% CI: 1.45-7.67), episiotomy (aOR 3.79, 95% CI: 2.20-6.52) and length of the second stage (aOR 00:18, 95% CI: 00:04-00:31). In neonatal outcomes, oxytocin in labor was associated with umbilical artery pH <= 7.20 (OR 3.29, 95% CI: 1.33-8.14). Admission to neonatal intensive care unit (OR 0.56, 95% CI: 0.22-1.42), neonatal resuscitation (OR 1.04, 95% CI: 0.22-1.42), and Apgar score <7 (OR 0.48, 95% CI: 0.17-1.33) were not associated with oxytocin administration during labor. Conclusions: Oxytocin administration during labor for low-risk women may lead to worse birth outcomes with an increased risk of instrumental birth and cesarean, episiotomy and the use of epidural analgesia for pain relief. Neonatal results may be also worse with an increased proportion of neonates displaying an umbilical arterial pH <= 7.20.

引用

页数：15

共 54 条

[1] Epidural versus non-epidural or no analgesia for pain management in labour (Review) [J].