Allylic alkylation versus Michael induced ring closure: Chelated enolates as versatile nucleophiles

被引：36

作者：

Pohlman, M ^{[1
]}

Kazmaier, U ^{[1
]}

Lindner, T ^{[1
]}

机构：

[1] Univ Saarland, Inst Organ Chem, D-66123 Saarbrucken, Germany

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2004年 / 69卷 / 20期

关键词：

D O I：

10.1021/jo049036q

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Allylic carbonates 8 bearing an electron-withdrawing ester functionality can act as substrates for palladium-catalyzed allylic alkylations or as Michael acceptors with the option to undergo subsequent ring closure. Chelated amino acid ester enolates 1' are versatile nucleophiles for both reactions giving high yields and selectivites.

引用

页码：6909 / 6912

页数：4

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