Thermal atropisomerism of fully functionalized vancomycin CD, DE, and CDE ring systems

被引：27
作者：
Boger, DL
Loiseleur, O
Castle, SL
Beresis, RT
Wu, JH
机构：
[1] Scripps Res Inst, Dept Chem, La Jolla, CA 92037 USA
[2] Scripps Res Inst, Skaggs Inst Chem Biol, La Jolla, CA 92037 USA
来源：
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1997年 / 7卷 / 24期
基金：
美国国家卫生研究院; 美国国家科学基金会;
关键词：
D O I：
10.1016/S0960-894X(97)10182-2
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
A study of the thermal atropisomerism of fully functionalized vancomycin CD, DE and CDE ring The studies suggested and resulted in the realization of a selective DE ring system atropisomerism of a fully functionalized vancomycin CDE ring system, offering a unique solution to the control of natural product atropisomer stereochemistry. (C) 1997 Elsevier Science Ltd.
引用
收藏
页码：3199 / 3202
页数：4
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