Long-Term Clinical Outcomes according to Initial Management and Thrombolysis In Myocardial Infarction Risk Score in Patients with Acute Non-ST-Segment Elevation Myocardial Infarction

被引：7

作者：

Jeong, Hae Chang

Ahn, Youngkeun ^{[17
]}

Jeong, Myung Ho

Chae, Shung Chull ^{[1
]}

Hur, Seung Ho ^{[2
]}

Hong, Taek Jong ^{[3
]}

Kim, Young Jo ^{[4
]}

Seong, In Whan ^{[5
]}

Chae, Jei Keon ^{[6
]}

Rhew, Jay Young ^{[7
]}

Chae, In Ho ^{[8
]}

Cho, Myeong Chan ^{[8
]}

Bae, Jang Ho ^{[9
]}

Rha, Seung Woon ^{[10
]}

Kim, Chong Jin ^{[11
]}

Choi, Donghoon ^{[12
]}

Jang, Yang Soo ^{[12
]}

Yoon, Junghan ^{[13
]}

Chung, Wook Sung ^{[14
]}

Cho, Jeong Gwan

Seung, Ki Bae ^{[15
]}

Park, Seung Jung ^{[16
]}

机构：

[1] Kyungpook Natl Univ, Dept Internal Med, Taegu, South Korea

[2] Keimyung Univ, Dongsan Med Ctr, Dept Internal Med, Taegu, South Korea

[3] Pusan Natl Univ Hosp, Dept Internal Med, Pusan, South Korea

[4] Yeungnam Univ Hosp, Dept Internal Med, Taegu, South Korea

[5] Chungnam Natl Univ Hosp, Dept Internal Med, Taejon, South Korea

[6] Chonbuk Natl Univ Hosp, Dept Internal Med, Jeonju, South Korea

[7] Jeonju Presbyterian Med Ctr, Dept Internal Med, Jeonju, South Korea

[8] Seoul Natl Univ, Bundang Hosp, Dept Internal Med, Songnam, South Korea

[9] Natl Univ, Dept Internal Med, Cheongju, South Korea

[10] Konyang Univ, Dept Internal Med, Taejon, South Korea

[11] Korea Univ, Guro Hosp, Dept Internal Med, Seoul, South Korea

[12] Kyung Hee Univ Hosp, Dept Internal Med, Seoul, South Korea

[13] Yonsei Univ, Wonju Hosp, Dept Internal Med, Wonju, South Korea

[14] Wonju Univ Hosp, Dept Internal Med, Wonju, South Korea

[15] Catholic Univ Hosp, Dept Internal Med, Seoul, South Korea

[16] Asan Med Ctr, Dept Internal Med, Seoul, South Korea

[17] Chonnam Natl Univ Hosp, Ctr Heart,KAMIR Study Grp Korean Circulat Soc, Stem Cell Res Ctr Cardiovasc & Neurol Disorders, Program Gene & Cell Therapy,Dept Internal Med, Kwangju 501757, South Korea

来源：

YONSEI MEDICAL JOURNAL | 2010年 / 51卷 / 01期

关键词：

Myocardial infarction; non-ST-segment elevation; invasive treatment; TIMI risk score; prognosis; ACUTE CORONARY SYNDROMES; UNSTABLE ANGINA; CONSERVATIVE STRATEGIES; GUIDELINE UPDATE; RANDOMIZED-TRIAL; TASK-FORCE; INTERVENTION; ASSOCIATION; STRATIFICATION; DEPRESSION;

D O I：

10.3349/ymj.2010.51.1.58

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Purpose: There is still debate about the timing of revascularization in patients with acute non-ST-segment elevation myocardial infarction (NSTEMI). We analyzed the long-term clinical outcomes of the timing of revascularization in patients with acute NSTEMI obtained from the Korea Acute Myocardial Infarction Registry (KAMIR). Materials and Methods: 2,845 patients with acute NSTEMI (65.6 +/- 12.5 years, 1,836 males) who were enrolled in KAMIR were included in the present study. The therapeutic strategy of NSTEMI was categorized into early invasive (within 48 hours, 65.8 +/- 12.6 years, 856 males) and late invasive treatment (65.3 +/- 12.1 years, 979 males). The initial- and long-term clinical outcomes were compared between two groups according to the level of Thrombolysis In Myocardial Infarction (TIMI) risk score. Results: There were significant differences in-hospital mortality and the incidence of major adverse cardiac events during one-year clinical follow-up between two groups (2.1% vs. 4.8%, p < 0.001, 10.0% vs. 13.5%, p = 0.004, respectively). According to the TIMI risk score, there was no significant difference of long-term clinical outcomes in patients with low to moderate TIMI risk score, but significant difference in patients with high TIMI risk score (>= 5 points). Conclusion: The old age, high Killip class, low ejection fraction, high TIMI risk score, and late invasive treatment strategy are the independent predictors for the long-term clinical outcomes in patients with NSTEMI.

引用

页码：58 / 68

页数：11

共 26 条

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