Long-Term Clinical Outcomes according to Initial Management and Thrombolysis In Myocardial Infarction Risk Score in Patients with Acute Non-ST-Segment Elevation Myocardial Infarction

被引:7
作者
Jeong, Hae Chang
Ahn, Youngkeun [17 ]
Jeong, Myung Ho
Chae, Shung Chull [1 ]
Hur, Seung Ho [2 ]
Hong, Taek Jong [3 ]
Kim, Young Jo [4 ]
Seong, In Whan [5 ]
Chae, Jei Keon [6 ]
Rhew, Jay Young [7 ]
Chae, In Ho [8 ]
Cho, Myeong Chan [8 ]
Bae, Jang Ho [9 ]
Rha, Seung Woon [10 ]
Kim, Chong Jin [11 ]
Choi, Donghoon [12 ]
Jang, Yang Soo [12 ]
Yoon, Junghan [13 ]
Chung, Wook Sung [14 ]
Cho, Jeong Gwan
Seung, Ki Bae [15 ]
Park, Seung Jung [16 ]
机构
[1] Kyungpook Natl Univ, Dept Internal Med, Taegu, South Korea
[2] Keimyung Univ, Dongsan Med Ctr, Dept Internal Med, Taegu, South Korea
[3] Pusan Natl Univ Hosp, Dept Internal Med, Pusan, South Korea
[4] Yeungnam Univ Hosp, Dept Internal Med, Taegu, South Korea
[5] Chungnam Natl Univ Hosp, Dept Internal Med, Taejon, South Korea
[6] Chonbuk Natl Univ Hosp, Dept Internal Med, Jeonju, South Korea
[7] Jeonju Presbyterian Med Ctr, Dept Internal Med, Jeonju, South Korea
[8] Seoul Natl Univ, Bundang Hosp, Dept Internal Med, Songnam, South Korea
[9] Natl Univ, Dept Internal Med, Cheongju, South Korea
[10] Konyang Univ, Dept Internal Med, Taejon, South Korea
[11] Korea Univ, Guro Hosp, Dept Internal Med, Seoul, South Korea
[12] Kyung Hee Univ Hosp, Dept Internal Med, Seoul, South Korea
[13] Yonsei Univ, Wonju Hosp, Dept Internal Med, Wonju, South Korea
[14] Wonju Univ Hosp, Dept Internal Med, Wonju, South Korea
[15] Catholic Univ Hosp, Dept Internal Med, Seoul, South Korea
[16] Asan Med Ctr, Dept Internal Med, Seoul, South Korea
[17] Chonnam Natl Univ Hosp, Ctr Heart,KAMIR Study Grp Korean Circulat Soc, Stem Cell Res Ctr Cardiovasc & Neurol Disorders, Program Gene & Cell Therapy,Dept Internal Med, Kwangju 501757, South Korea
关键词
Myocardial infarction; non-ST-segment elevation; invasive treatment; TIMI risk score; prognosis; ACUTE CORONARY SYNDROMES; UNSTABLE ANGINA; CONSERVATIVE STRATEGIES; GUIDELINE UPDATE; RANDOMIZED-TRIAL; TASK-FORCE; INTERVENTION; ASSOCIATION; STRATIFICATION; DEPRESSION;
D O I
10.3349/ymj.2010.51.1.58
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Purpose: There is still debate about the timing of revascularization in patients with acute non-ST-segment elevation myocardial infarction (NSTEMI). We analyzed the long-term clinical outcomes of the timing of revascularization in patients with acute NSTEMI obtained from the Korea Acute Myocardial Infarction Registry (KAMIR). Materials and Methods: 2,845 patients with acute NSTEMI (65.6 +/- 12.5 years, 1,836 males) who were enrolled in KAMIR were included in the present study. The therapeutic strategy of NSTEMI was categorized into early invasive (within 48 hours, 65.8 +/- 12.6 years, 856 males) and late invasive treatment (65.3 +/- 12.1 years, 979 males). The initial- and long-term clinical outcomes were compared between two groups according to the level of Thrombolysis In Myocardial Infarction (TIMI) risk score. Results: There were significant differences in-hospital mortality and the incidence of major adverse cardiac events during one-year clinical follow-up between two groups (2.1% vs. 4.8%, p < 0.001, 10.0% vs. 13.5%, p = 0.004, respectively). According to the TIMI risk score, there was no significant difference of long-term clinical outcomes in patients with low to moderate TIMI risk score, but significant difference in patients with high TIMI risk score (>= 5 points). Conclusion: The old age, high Killip class, low ejection fraction, high TIMI risk score, and late invasive treatment strategy are the independent predictors for the long-term clinical outcomes in patients with NSTEMI.
引用
收藏
页码:58 / 68
页数:11
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