Rate of the "burnt-out diabetes" phenomenon in patients on peritoneal dialysis

被引：6

作者：

Abe, Masanori ^{[1
,2
]}

Hamanno, Takayuki ^{[1
,3
]}

Hoshino, Junichi ^{[1
,4
]}

Wada, Atsushi ^{[1
,5
]}

Nakai, Shigeru ^{[1
,6
]}

Masakane, Ikuto ^{[1
,7
]}

机构：

[1] JSDT, JSDT Renal Data Registry Comm JRDR Comm, Tokyo, Japan

[2] Nihon Univ, Dept Internal Med, Sch Med, Div Nephrol Hypertens & Endocrinol, Tokyo, Japan

[3] Osaka Univ, Dept Inter Organ Commun Res Kidney Dis, Grad Sch Med, Osaka, Japan

[4] Toranomon Gen Hosp, Nephrol Ctr, Tokyo, Japan

[5] Kitasaito Hosp, Dept Nephrol, Asahikawa, Hokkaido, Japan

[6] Fujita Hlth Univ, Dept Clin Engn, Aichi, Japan

[7] Yabuki Hosp, Yamagata, Japan

来源：

DIABETES RESEARCH AND CLINICAL PRACTICE | 2018年 / 143卷

关键词：

Diabetes; Glycemic control; Glycated albumin; Glycated hemoglobin; Peritoneal dialysis; PREDIALYSIS GLYCEMIC CONTROL; GLYCATED ALBUMIN; INDEPENDENT PREDICTOR; HEMODIALYSIS-PATIENTS; HEMOGLOBIN; MORTALITY; SURVIVAL; RISK; ASSOCIATION; MELLITUS;

D O I：

10.1016/j.diabres.2018.07.026

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Aims: In some diabetes patients on dialysis, glycemic control improves spontaneously, leading to normal HbA1c levels; this phenomenon is known as "burnt-out diabetes." Glycated albumin (GA) might be a better indicator of glycemic control than HbA1c in hemodialysis patients, but it has not been assessed in peritoneal dialysis (PD) patients. Methods: This study involved diabetes patients on PD, with HbA1c level and antidiabetes therapy records. First, the "burnt-out diabetes" phenomenon was investigated in patients with HbA1c measurements alone (HbA1c cohort). Then, it was investigated in patients with both HbA1c and GA measurements (GA cohort). Results: A total of 1296 patients were included in the HbA1c cohort. When "burnt-out diabetes" was defined as HbA1c < 6.0% without treatment, it was noted in 269 patients (20.8%). A total of 413 patients were subsequently included in the GA cohort. "Burnt-out diabetes," using the same definition, was found in 73 patients (17.7%). However, when defined as HbA1c < 6.0% and GA < 16.0% without treatment, "burnt-out diabetes" was found in 45 patients (10.9%). Conclusions: Although the "burnt-out diabetes" phenomenon was present in 17.7% of patients with diabetes on PD based on HbA1c, the rate was significantly decreased to 10.9% when taking GA into account. (C) 2018 Elsevier B.V. All rights reserved.

引用

页码：254 / 262

页数：9

共 27 条

[1] Glycated hemoglobin or glycated albumin for assessment of glycemic control in hemodialysis patients with diabetes? [J].