Recent advances in bioactive 1D and 2D carbon nanomaterials for biomedical applications

被引：92

作者：

Erol, Ozlem ^{[1
]}

Uyan, Idil ^{[1
,3
]}

Hatip, Meryem ^{[1
,2
]}

Yilmaz, Canelif ^{[1
,3
]}

Tekinay, Ayse B. ^{[1
,2
,3
]}

Guler, Mustafa O. ^{[1
,2
,4
]}

机构：

[1] Bilkent Univ, Natl Nanotechnol Res Ctr UNAM, Ankara, Turkey

[2] Bilkent Univ, Inst Mat Sci & Nanotechnol, Ankara, Turkey

[3] Bilkent Univ, Neurosci Program, Ankara, Turkey

[4] Univ Chicago, Inst Mol Engn, Chicago, IL 60637 USA

来源：

NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE | 2018年 / 14卷 / 07期

关键词：

Carbon nanotube; Graphene; Graphene oxide; Biomedical applications; Biocompatibility; MESENCHYMAL STEM-CELLS; SINGLE-WALLED NANOTUBES; GRAPHENE OXIDE; OSTEOGENIC DIFFERENTIATION; ELECTRICAL-STIMULATION; NANOSTRUCTURED CARBON; IN-VITRO; MYOBLAST DIFFERENTIATION; FUNCTIONALIZED GRAPHENE; PHOTOTHERMAL THERAPY;

D O I：

10.1016/j.nano.2017.03.021

中图分类号：

TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

One-dimensional (1D) carbon nanotubes (CNTs) and the two-dimensional (2D) graphene represent the most widely studied allotropes of carbon. Due to their unique structural, electrical, mechanical and optical properties, 1D and 2D carbon nanostructures are considered to be leading candidates for numerous applications in biomedical fields, including tissue engineering, drug delivery, bioimaging and biosensors. The biocompatibility and toxicity issues associated with these nanostructures have been a critical impediment for their use in biomedical applications. In this review, we present an overview of the various materials types, properties, functionalization strategies and characterization methods of 1D and 2D carbon nanomaterials and their derivatives in terms of their biomedical applications. In addition, we discuss various factors and mechanisms affecting their toxicity and biocompatibility. (c) 2017 Elsevier Inc. All rights reserved.

引用

页码：2433 / 2454

页数：22

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