Factors associated to loss of follow-up in patients underwent antiretroviral therapy in an ambulatory HIV treatment center at Conakry

被引：2

作者：

Toure, A. ^{[1
]}

Cisse, D. ^{[1
]}

Kadio, K. J. J. O. ^{[1
]}

Camara, A. ^{[1
]}

Traore, F. A. ^{[2
]}

Delamou, A. ^{[1
]}

Sidide, S. ^{[1
]}

Kouyate, C. ^{[3
]}

Bangoura, I. S. ^{[3
]}

Diallo, M. M. ^{[4
]}

Tounkara, T. M. ^{[5
]}

Traore, F. ^{[6
]}

Sow, M. S. ^{[2
]}

Khanafer, N. ^{[7
]}

Cisse, M. ^{[5
]}

机构：

[1] Univ Gamal Abdel Nasser Conakryf, Fac Med Pharm Odonto Stomatol, Chaire Sante Publ, BP 1017, Conakry, Guinea

[2] Hop Natl Donka, Serv Malad Infect & Trop, Conakry, Guinea

[3] Assoc Femmes Guinee Lutte IST & Sida ASFEGMASSI, Conakry, Guinea

[4] Solidarite Therapeut & Initiat Sante Solthis, Conakry, Guinea

[5] Hop Natl Donka, Serv Dermatol Venerol MST, Conakry, Guinea

[6] Inst Natl Sante Publ, Conakry, Guinea

[7] Hosp Civils Lyon, Hop Edouard Herriot, Epidemiol & Infect Control Unit, F-69003 Lyon, France

来源：

REVUE D EPIDEMIOLOGIE ET DE SANTE PUBLIQUE | 2018年 / 66卷 / 04期

关键词：

HIV; HAART; Loss to follow-up; Guinea; INFECTED PATIENTS; OUTCOMES; SURVIVAL; ETHIOPIA; AFRICA; CARE;

D O I：

10.1016/j.respe.2018.04.057

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Background. - Late or inadequate therapeutic management increases the risk of mortality associated with HIV/AIDS. The aim of this study was to analyze the proportion and factors associated with loss of follow-up in HIV patients who receiving antiretroviral therapy at Conakry. Methods. - A retrospective cohort study was conducted in HIV patients aged over 15 years and who receiving antiretroviral therapy. Between August 1, 2008 and July 31, 2015, all patients managed by the ambulatory treatment center of the Guinean Women Association against AIDS and sexually and transmissible infection were included. Loss of follow-up was defined as no follow-up visit within 3 months. Kaplan-Meier curves and multivariate Cox regression models were used to analyze factors associated with loss of follow-up. Analyses were performed by using Stata 13 software. Results. - 614 patients aged 36.3 +/- 11.2 years, mainly females (68.4%) and living in Conakry (80.5%) were included. Among them, 104 were loss to follow-up, corresponding to a proportion rate of 16.9% (95% CI: 14.2-19.7%) or 5.79/100 person-years. The results of multivariate analyses showed that factors independently associated with loss of follow-up were malnutrition (AHR = 7.05; 95% CI: 2.05-24.27; P = 0.002) and CD4 cells account at the initiation of AHR (2.35; 95% CI: 1.61-6.39; P = 0.016) in patients with 201-350 CD4/mu L and 5.83 (95% CI: 2.85-11.90; P < 0.001) in patients with less than 150 CD4/mu L. Conclusion. - Despite efforts of health care workers and free antiretroviral therapy, many patients were loss to follow-up. Multivariate analysis showed that malnutrition and low CD4 account were independently associated with loss to follow-up. (C) 2018 Elsevier Masson SAS. All rights reserved.

引用

页码：273 / 279

页数：7