Structures of amamistatins A and B, novel growth inhibitors of human tumor cell lines from Nocardia asteroides

被引：31

作者：

Kokubo, S

Suenaga, K

Shinohara, C

Tsuji, T

Uemura, D ^{[1
]}

机构：

[1] Nagoya Univ, Grad Sch Sci, Dept Chem, Chikusa Ku, Nagoya, Aichi 4648602, Japan

[2] Sagami Chem Res Ctr, Sagamihara, Kanagawa 2290012, Japan

来源：

TETRAHEDRON | 2000年 / 56卷 / 35期

关键词：

peptides; oxazoles; degradation; stereochemistry;

D O I：

10.1016/S0040-4020(00)00591-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Two new lipopeptides, amamistatins A and B, were isolated from Nocardia asteroides SCRC-A2359,and their absolute stereostructures were determined by spectroscopic and chemical analyses. Amamistatin A inhibited the growth of human tumor cell lines. (C) 2000 Elsevier Science Ltd. All rights reserved.

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收藏

页码：6435 / 6440

页数：6

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