Fatigue in older adults: an early indicator of the aging process?

被引：158

作者：

Avlund, Kirsten ^{[1
,2
,3
,4
,5
]}

机构：

[1] Univ Copenhagen, Dept Social Med, Inst Publ Hlth, DK-1014 Copenhagen K, Denmark

[2] Res Ctr Prevent & Hlth, Copenhagen, Denmark

[3] Univ Aarhus, Danish Aging Res Ctr, Odense, Denmark

[4] Univ Copenhagen, Danish Aging Res Ctr, DK-1014 Copenhagen K, Denmark

[5] Univ Copenhagen, Ctr Healthy Aging, DK-1014 Copenhagen K, Denmark

来源：

AGING CLINICAL AND EXPERIMENTAL RESEARCH | 2010年 / 22卷 / 02期

关键词：

Disability; fatigue; frailty; functional limitations; NECROSIS-FACTOR-ALPHA; HEALTH SURVEY SF-36; FUNCTIONAL ABILITY; VITAL EXHAUSTION; MUSCLE STRENGTH; INFLAMMATORY MARKERS; MUSCULOSKELETAL DISEASES; DEVELOPMENTAL ORIGINS; PHYSICAL PERFORMANCE; SCALING ASSUMPTIONS;

D O I：

10.1007/BF03324782

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

The aim of this paper is to give an overview of research on fatigue in older adults, with a focus on fatigue as an early indicator of the aging process. Fatigue is a strong predictor of functional limitations, disability, mortality, and other adverse outcomes in young-old and old-old populations, between men and women, and in different geographic localities. Several biological, physiological and social explanations are proposed: fatigue may be seen not only as a self-reported indicator of frailty, defined as a physiologic state of increased vulnerability to stressors, which results from decreased physiologic reserves and even dysregulation of multiple physiologic systems, but also this state may be accelerated because of the cumulative impact of social, mental and biological factors throughout life. (Aging Clin Exp Res 2010: 22: 100-115) (C) 2010. Editrice Kurtis

引用

页码：100 / 115

页数：16

共 156 条

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