Advances in pancreas transplantation

被引:33
作者
Dholakia, Shamik [1 ]
Oskrochi, Youssof [2 ]
Easton, Graham [2 ]
Papalois, Vassilios [1 ]
机构
[1] Imperial Coll Healthcare NHS Trust, West London Renal & Transplant Ctr, London W12 0HS, England
[2] Univ London Imperial Coll Sci Technol & Med, Dept Publ Hlth & Primary Care, London W6 8RP, England
关键词
Chronic diseases; endocrinology; evidence-based practice; surgery; KIDNEY-TRANSPLANTATION; COMPLICATIONS; OUTCOMES;
D O I
10.1177/0141076816636369
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The potential to reverse diabetes has to be balanced against the morbidity of long-term immunosuppression associated with transplantation. For a patient with renal failure, the treatment of choice is often a simultaneous transplant of the pancreas and kidney or pancreas after kidney. For a patient with glycaemic instability, choices between a solid organ or islet transplant have to be weighed against benefits and risks of remaining on insulin. Results of simultaneous transplant of the pancreas and kidney transplantation are comparable to other solid-organ transplants, and there is evidence of improved quality of life and life expectancy. There is some evidence of benefit with respect to the progression of secondary diabetic complications in patients with functioning transplants for several years.
引用
收藏
页码:141 / 146
页数:6
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