Microevolution in genomic short sequence repeats of Candida albicans in non-neutropenic patients

被引：5

作者：

Al-Aidan, Al Waleed

Goessens, Wil

Toom, Nicole Lemmens-den

Al-Ahdal, Mohammed

van Belkum, Alex

机构：

[1] Erasmus MC, Dept Med Microbiol & Infect Dis, NL-3015 GD Rotterdam, Netherlands

[2] King Faysal Hosp & Res Ctr, Dept Microbiol & Hosp Hyg, Riyadh, Saudi Arabia

来源：

YEAST | 2007年 / 24卷 / 03期

关键词：

Candida albicans; VNTR; SSR; infection; trauma patients;

D O I：

10.1002/yea.1462

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The genome of the yeast Candida albicans harbours many genomic short sequence repeats (SSRs). These are stable upon transition of colonization to infection in immune-compromised patients. We show here that in non-neutropenic patients this transition may coincide with variation in several of the SSRs. This may have implications for stage-specific expression of C. albicans pathogenicity factors. Copyright (c) 2007 John Wiley & Sons, Ltd.

引用

页码：155 / 160

页数：6

共 24 条

[1] Management of invasive candidiasis in critically ill patients [J].

Blot, S ;

Vandewoude, K .

DRUGS, 2004, 64 (19) :2159-2175

[2] Typing Candida albicans oral isolates from human immunodeficiency virus-infected patients by multilocus enzyme electrophoresis and DNA fingerprinting [J].

Boerlin, P ;

BoerlinPetzold, F ;

Goudet, J ;

Durussel, C ;

Pagani, JL ;

Chave, JP ;

Bille, J .

JOURNAL OF CLINICAL MICROBIOLOGY, 1996, 34 (05) :1235-1248

[3] Usefulness of multilocus sequence typing for characterization of clinical isolates of Candida albicans [J].

Bougnoux, ME ;

Morand, S ;

d'Enfert, C .

JOURNAL OF CLINICAL MICROBIOLOGY, 2002, 40 (04) :1290-1297

[4] A human-curated annotation of the Candida albicans genome [J].

Braun, BR ;

Hoog, MV ;

d'Enfert, C ;

Martchenko, M ;

Dungan, J ;

Kuo, A ;

Inglis, DO ;

Uhl, MA ;

Hogues, H ;

Berriman, M ;

Lorenz, M ;

Levitin, A ;

Oberholzer, U ;

Bachewich, C ;

Harcus, D ;

Marcil, A ;

Dignard, D ;

Iouk, T ;

Zito, R ;

Frangeul, L ;

Tekaia, F ;

Rutherford, K ;

Wang, E ;

Munro, CA ;

Bates, S ;

Gow, NA ;

Hoyer, LL ;

Köhler, G ;

Morschhäuser, J ;

Newport, G ;

Znaidi, S ;

Raymond, M ;

Turcotte, B ;

Sherlock, G ;

Costanzo, M ;

Ihmels, J ;

Berman, J ;

Sanglard, D ;

Agabian, N ;

Mitchell, AP ;

Johnson, AD ;

Whiteway, M ;

Nantel, A .

PLOS GENETICS, 2005, 1 (01) :36-57

[5]

BROSS J, 1989, AM J MED, V87, P614, DOI 10.1016/S0002-9343(89)80392-4

[6] Microsatellites in the eukaryotic DNA mismatch repair genes as modulators of evolutionary mutation rate [J].

Chang, DK ;

Metzgar, D ;

Wills, C ;

Boland, CR .

GENOME RESEARCH, 2001, 11 (07) :1145-1146

[7] Use of polymorphic short and clustered coding-region microsatellites to distinguish strains of Candida albicans [J].

Field, D ;

Eggert, L ;

Metzgar, D ;

Rose, R ;

Wills, C .

FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY, 1996, 15 (2-3) :73-79

[8]

FONZI WA, 1993, GENETICS, V134, P717

[9] A DNA polymorphism specific to Candida albicans strains exceptionally successful as human pathogens [J].

Giblin, L ;

Edelmann, A ;

Zhang, NX ;

von Maltzahn, NB ;

Cleland, SB ;

Sullivan, PA ;

Schmid, J .

GENE, 2001, 272 (1-2) :157-164

[10] Stability of allelic frequencies and distributions of Candida albicans microsatellite loci from US population-based surveillance isolates [J].

Lott, TJ ;

Fundyga, RE ;

Brandt, ME ;

Harrison, LH ;

Sofair, AN ;

Hajjeh, RA ;

Warnock, DW .

JOURNAL OF CLINICAL MICROBIOLOGY, 2003, 41 (03) :1316-1321

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