Lignans from Linum species of sections Syllinum and Linum

被引:30
作者
Konuklugil, B.
Ionkova, I.
Vasilev, N.
Schmidt, T. J.
Windhoevel, J.
Fuss, E.
Alfermann, A. W.
机构
[1] Inst Entwicklungs & Mol Biol Pflanzen, D-40225 Dusseldorf, Germany
[2] Hacettepe Univ, Fac Pharm, TR-06100 Tandogan, Turkey
[3] Med Univ Sofia, Fac Pharm, Sofia 1000, Bulgaria
[4] Univ Munster, Inst Pharmazeut Biol & Phytochem, D-48199 Munster, Germany
关键词
Linum; podophyllotoxin; 6-methoxypodophyllotoxin; 5 '-demethoxy-6-methoxy-podophyllotoxin; 4 '-demethyl-6-methoxypodophyllotoxin; 6-methoxypicropodophyllin; 5 '-demethoxy-6-methoxypicropodophyllin; justicidin B; isojusticidin B;
D O I
10.1080/14786410600798385
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
The aryltetralin lignans 6-methoxypodophyllotoxin, 5'-demethoxy-6-methoxypodophyllotoxin as well as the corresponding 8'-epimers 6-methoxypicropodophyllin, and 5'-demethoxy-6-methoxypicropodophyllin were isolated from suspension cultures of Linum cariense, and 4'-demethyl-6-methoxypodophyllotoxin together with 6-methoxypodophyllotoxin from plants of L. tauricum, which both belong to section Syllinum of the genus Linum. Cell cultures of L. altaicum, L. austriacum ssp. euxinum and L. lewisii belonging to section Linum accumulate the naphthalene lignans justicidin B and isojusticidin B. The different lignans were identified by HPLC and spectroscopic methods.
引用
收藏
页码:1 / 6
页数:6
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