Multicentric genetic study of Candida albicans isolates from non-neutropenic patients using MLEE typing:: population structure and mode of reproduction

被引：13
|
作者：
Arnavielhe, S
De Meeüs, T
Blancard, A
Mallié, M
Renaud, F
Bastide, JM
机构：
[1] Fac Pharm Montpellier, Lab Immunol Parasitol, Montpellier, France
[2] Hop Enfants La Timone, Lab Mycol & Parasitol, Marseille, France
来源：
MYCOSES | 2000年 / 43卷 / 3-4期
关键词：
Candida albicans; neutropenia; multilocus enzyme electrophoresis; MLEE; nosocomial infection;
D O I：
10.1046/j.1439-0507.2000.00552.x
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
A mycological survey was conducted on non-neutropenic patients in three distinct intensive care units in two hospitals in Marseille (France) from November 1993 to November 1995. Candida albicans positive cultures from 62 patients were included in this study. Every first isolate of each patient was typed by multilocus enzyme electrophoresis (MLEE). The enzyme profiles obtained from 15 polymorphic loci were then compared. This analysis demonstrated a strong population differentiation of C, albicans infective strains within and between the different care units and confirmed the probable preponderant clonal mode of reproduction of this yeast.
引用
收藏
页码：109 / 117
页数：9
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