The Hammersmith Hospital hematopathology case of the month: Myeloid sarcoma with Langerhans cell proliferation

被引:2
作者
Naresh, Kikkeri N. [1 ]
Zokaie, Simon [2 ]
Madhavan, Krishna Swamy [3 ]
Chu, Anthony [2 ]
机构
[1] Imperial Coll Healthcare NHS Trust & Imperial Col, Dept Histopathol, London W12 0HS, England
[2] Imperial Coll Healthcare NHS Trust & Imperial Col, Dept Dermatol, London W12 0HS, England
[3] Southend Univ Hosp, Dept Oncol, Westcliff On Sea, Essex, England
关键词
Myeloid sarcoma; acute myeloid leukemia; granulocytic sarcoma; Langerhans cell; Langerhans cell histiocytosis; histiocytosis; ACUTE-LEUKEMIA; HISTIOCYTOSIS; ASSOCIATION; DISORDERS;
D O I
10.3109/10428191003777989
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
We present a patient whose initial lymph node biopsy showed extensive histiocyte and Langerhans cell infiltration, which obscured the underlying myeloid sarcoma (MS). The initial diagnosis of Langerhans cell histiocytosis (LCH) was not compatible with the disease evolution, and a subsequent biopsy performed much later showed all the characteristics of MS. Clinical distinction between LCH and MS involving the skin and management of these diseases, and the reported association of LCH/Langerhans cell proliferations with myeloid and lymphoid malignancies, are discussed.
引用
收藏
页码:1128 / 1134
页数:7
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