Chemical Composition Effect of Sol-Gel Derived Bioactive Glass Over Bioactivity Behavior

被引：2

作者：

Quintero, L. A. ^{[1
]}

Escobar, D. M. ^{[1
]}

机构：

[1] Univ Antioquia, Biomat Res Grp, Engn Fac, St 70 52-21, Medellin, Colombia

来源：

PROCEEDINGS OF THE 3RD PAN AMERICAN MATERIALS CONGRESS | 2017年

关键词：

Bioactive glasses; Apatite layer; Bone tissue engineering; SBF;

D O I：

10.1007/978-3-319-52132-9_2

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Bioactive glasses (BG) are a group of inorganic materials widely used in Bone Tissue Engineering (BTE). These biomaterials react with body fluids resulting in the formation of bone like apatite layer. In this study, sol-gel derived bioactive glass was synthesized in the SiO2-CaO-P2O5 system according to augmented constrained mixture experimental design, with percentage restrictions for each oxide as follows: 58 <= SiO2 <= 70; 6 <= P2O5 <= 9 and 24 <= CaO <= 34. BG were conformed into short-bulk cylinders and immersed in Simulated Body Fluid (SBF) solution for 7 and 14 days in order to carry out bioactivity tests. Apatite layer formation was confirmed by Scanning Electron Microscopy (SEM) and Energy Dispersive X-ray Analysis (EDX). The results showed apatite layer formation depended on BG chemical composition proved with p-values from ANOVA analysis below 0.05 indicating factors significance over the response. The formed apatite layer presented a Ca/P ratio similar to bone apatite, this result is appropriate for biomaterials used in BTE.

引用

页码：11 / 19

页数：9

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