Lithium neurotoxicity presenting as dementia with therapeutic serum lithium levels

被引:7
作者
Soni, Sarita [1 ]
机构
[1] NHS Greater Glasgow & Clyde, Dept Learning Disabil, Glasgow, Lanark, Scotland
关键词
psychiatry (drugs And Medicines); unwanted effects; adverse reactions; psychiatry; drugs: psychiatry; mood disorders (including depression);
D O I
10.1136/bcr-2018-227741
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
After 25 years of continuous lithium therapy, a woman with moderate intellectual disability and bipolar disorder developed symptoms suggestive of dementia. In fact, she had developed lithium neurotoxicity, but this was overlooked for 18 months as serial lithium levels were in the therapeutic range.
引用
收藏
页数:3
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共 17 条
[1]   Lithium-induced neurotoxicity at serum lithium levels within the therapeutic range [J].
Arya, DK .
AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY, 1996, 30 (06) :871-873
[2]   LITHIUM NEUROTOXICITY AT NORMAL THERAPEUTIC LEVELS [J].
BELL, AJ ;
COLE, A ;
ECCLESTON, D ;
FERRIER, IN .
BRITISH JOURNAL OF PSYCHIATRY, 1993, 162 :689-692
[3]   The effectiveness of mood stabilizers and antiepileptic medication for the management of behaviour problems in adults with intellectual disability: a systematic review [J].
Deb, S. ;
Chaplin, R. ;
Sohanpal, S. ;
Unwin, G. ;
Soni, R. ;
Lenotre, L. .
JOURNAL OF INTELLECTUAL DISABILITY RESEARCH, 2008, 52 :107-113
[4]   COMPARISON OF STANDARD AND LOW SERUM LEVELS OF LITHIUM FOR MAINTENANCE TREATMENT OF BIPOLAR DISORDER [J].
GELENBERG, AJ ;
KANE, JM ;
KELLER, MB ;
LAVORI, P ;
ROSENBAUM, JF ;
COLE, K ;
LAVELLE, J .
NEW ENGLAND JOURNAL OF MEDICINE, 1989, 321 (22) :1489-1493
[5]  
Goyal R, 2014, J CLIN PSYCHOPHARM, V34, pE4, DOI 10.1097/JCP.0000000000000181
[6]   Neurotoxicity with Therapeutic Lithium Levels: A Case Report [J].
Grueneberger, Elizabeth C. ;
Rountree, E. Maria ;
Short, E. Baron ;
Kahn, David A. .
JOURNAL OF PSYCHIATRIC PRACTICE, 2009, 15 (01) :60-63
[7]   Uptake of lithium into rat brain after acute and chronic administration [J].
Hillert, Markus ;
Zimmermann, Martina ;
Klein, Jochen .
NEUROSCIENCE LETTERS, 2012, 521 (01) :62-66
[8]   REVERSIBLE LITHIUM NEUROTOXICITY AT NORMAL SERUM LEVEL MAY REFER TO INTRACRANIAL PATHOLOGY [J].
KEMPERMAN, CJF ;
GERDES, JH ;
DEROOIJ, J ;
VENCKEN, LM .
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 1989, 52 (05) :679-680
[9]   Potential Mechanisms of Action of Lithium in Bipolar Disorder Current Understanding [J].
Malhi, Gin S. ;
Tanious, Michelle ;
Das, Pritha ;
Coulston, Carissa M. ;
Berk, Michael .
CNS DRUGS, 2013, 27 (02) :135-153
[10]  
Mesquita J, 2010, J NEUROPSYCH CLIN N, V22, pE29