Treponema pallidum pallidum Genotypes and Macrolide Resistance Status in Syphilitic Lesions among Patients at 2 Sexually Transmitted Infection Clinics in Lima, Peru

被引：17

作者：

Antonio Flores, Juan ^{[1
]}

Keith Vargas, Silver ^{[1
]}

Ramos Leon, Segundo ^{[1
]}

Giancarlo Perez, Danny ^{[1
]}

Beatriz Ramos, Lourdes ^{[1
]}

Chow, Jeremy ^{[2
]}

Konda, Kelika Anne ^{[2
]}

Mauricio Calvo, Gino ^{[3
]}

Salvatierra, Hector J. ^{[4
]}

Klaussner, Jeffrey D. ^{[2
]}

Fernando Caceres, Carlos ^{[3
]}

机构：

[1] Univ Peruana Cayetano Heredia, Lab Sexual Hlth, Ctr Interdisciplinary Res Sexual AIDS & Soc, Lima 31, Peru

[2] Univ Calif Los Angeles, David Geffen Sch Med, Program Global Hlth, Div Infect Dis, Los Angeles, CA 90095 USA

[3] Univ Peruana Cayetano Heredia, Ctr Interdisciplinary Res Sexual AIDS & Soc, Lima 31, Peru

[4] Alberto Barton Clin, Callao, Peru

来源：

SEXUALLY TRANSMITTED DISEASES | 2016年 / 43卷 / 07期

关键词：

AZITHROMYCIN RESISTANCE; SECONDARY SYPHILIS; TREATMENT FAILURE; SUBSP PALLIDUM; MEN; PCR; PREVALENCE; SHANGHAI; SEX;

D O I：

10.1097/OLQ.0000000000000465

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

We report the circulating genotypes and the frequency of macrolide-resistance patterns among Treponema pallidum pallidum DNA isolated from syphilitic lesions from patients who attended 2 sexual health clinics in Lima, Peru. We implemented and used amolecular typing scheme to describe local T. pallidum pallidum strains. Among 14 specimens, subtype 14d/f was the most prevalent strain in 7 fully typed T. pallidum DNA specimens obtained from men who have sex with men and transgender women presenting with chancre-like lesions. No macrolide-resistance mutations were found in T. pallidum DNA from 10 lesions.

引用

页码：465 / 466

页数：2

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