Retrospective analysis of related factors affecting skin wound healing

被引:0
|
作者
Chen, Xin [1 ]
Zhou, Xin [1 ]
Xia, Xin [1 ]
Chen, Yao [1 ]
Mao, Tongchun [1 ]
Shi, Xiaohua [1 ]
Zhang, Yiming [1 ]
Fan, Dongli [1 ]
机构
[1] Third Mil Med Univ, Xinqiao Hosp, Dept Plast & Cosmet Surg, Xinqiao Rd, Chongqing 400037, Peoples R China
来源
INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE | 2018年 / 11卷 / 08期
基金
中国国家自然科学基金;
关键词
Wound; surgical treatment; related factors; retrospective analysis; CUTANEOUS SCARRING PATHOPHYSIOLOGY; MOLECULAR-MECHANISMS; DERMAL FIBROBLASTS; REGENERATION; STRATEGIES; MANAGEMENT; CELLS;
D O I
暂无
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Objective: The aim of this study was to investigate the related factors in wound healing and to provide clinical evidence for the prevention and treatment of skin wounds, especially refractory wounds. Methods: Five hundred sixty-seven wound cases that were treated at the Department of Plastic and Cosmetic Surgery of Xing iao Hospital in Chongqing, China, from January 2003 to December 2016, were retrospectively reviewed, and the related factors were analyzed using Logistic regression. Results: Single factor analysis of the related factors showed that 7 related factors, namely, age, wound area, wound type, cause of wound formation, surgical treatment, the time from wound formation to surgical treatment and the use of vacuum sealing drainage (VSD), were the influencing factors. Logistic regression analysis showed that there were no significant differences in age, wound type, cause of wound formation or surgical treatment (P > 0.05); however, the time from wound formation to surgical treatment and the use of VSD were the most influential factors affecting wound healing (P < 0.05). Conclusion: The efficacy of wound healing is affected by many factors. According to the type of wound, different treatment plans should be established, the infection should be prevented, and attention should be paid to the treatment time, such that wounds are treated as soon as possible. For the conditioned wound, the technique of VSD can be applied to shorten the healing time, promote wound healing and improve the healing rate of the wound.
引用
收藏
页码:8615 / 8621
页数:7
相关论文
共 50 条
  • [21] Proinflammatory Cytokines and Skin Wound Healing in Mice
    M. A. Nosenko
    S. G. Ambaryan
    M. S. Drutskaya
    Molecular Biology, 2019, 53 : 653 - 664
  • [22] Heat delays skin wound healing in mice
    dos Santos-Silva, Marco Aurelio
    Lima Trajano, Eduardo Tavares
    Schanuel, Fernanda Seabra
    Monte-Alto-Costa, Andrea
    EXPERIMENTAL BIOLOGY AND MEDICINE, 2017, 242 (03) : 358 - 266
  • [23] Zwitterionic hydrogels promote skin wound healing
    Zhu, Yingnan
    Zhang, Jiamin
    Yang, Jing
    Pan, Chao
    Xu, Tong
    Zhang, Lei
    JOURNAL OF MATERIALS CHEMISTRY B, 2016, 4 (30) : 5105 - 5111
  • [24] The Role of Extracellular Matrix in Skin Wound Healing
    Potekaev, Nikolai N.
    Borzykh, Olga B.
    Medvedev, German V.
    Pushkin, Denis V.
    Petrova, Marina M.
    Petrov, Artem V.
    Dmitrenko, Diana V.
    Karpova, Elena I.
    Demina, Olga M.
    Shnayder, Natalia A.
    JOURNAL OF CLINICAL MEDICINE, 2021, 10 (24)
  • [25] Topical 5-azacytidine accelerates skin wound healing in rats
    Gomes, Fabiana S.
    de-Souza, Gabriela F.
    Nascimento, Lucas F.
    Arantes, Eva L.
    Pedro, Rafael M.
    Vitorino, Daniele C.
    Nunez, Carla E.
    Melo Lima, Maria H.
    Velloso, Licio A.
    Araujo, Eliana P.
    WOUND REPAIR AND REGENERATION, 2014, 22 (05) : 640 - 646
  • [26] The complex role of skin microbiota in wound healing
    Bonte, Frederic
    Pasamon, Mathilde
    Desmouliere, Alexis
    ACTUALITES PHARMACEUTIQUES, 2022, 61 (619): : 33 - 38
  • [27] Modelling skin wound healing angiogenesis: A review
    Guerra, Ana
    Belinha, Jorge
    Jorge, Renato Natal
    JOURNAL OF THEORETICAL BIOLOGY, 2018, 459 : 1 - 17
  • [28] ROS-scavenging materials for skin wound healing: advancements and applications
    Dong, Yongkang
    Wang, Zheng
    FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 2023, 11
  • [29] Potential Role of AGR2 for Mammalian Skin Wound Healing
    Kosykh, Anastasiya V.
    Tereshina, Maria B.
    Gurskaya, Nadya G.
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 24 (09)
  • [30] Retrospective analysis of factors affecting the efficacy of surgical treatment of the scar
    Yang, Z.
    Shi, X.
    Zhang, Y.
    Wang, S.
    Lei, Z.
    Liu, X.
    Fan, D.
    MINERVA CHIRURGICA, 2014, 69 (02) : 83 - 89