Post-operative complications due to salvage total laryngectomy for recurrent laryngeal cancer after radiotherapy - a multicentre retrospective study

被引：2

作者：

Okamoto, Isaku ^{[1
]}

Matsuki, Takashi ^{[2
]}

Sato, Hiroki ^{[1
]}

Kondo, Takahito ^{[3
]}

Fushimi, Chihiro ^{[4
]}

Okada, Takuro ^{[4
]}

Miura, Kouki ^{[4
]}

Yamashita, Taku ^{[2
]}

Omura, Go ^{[5
]}

Tsukahara, Kiyoaki ^{[1
]}

机构：

[1] Tokyo Med Univ, Dept Otorhinolaryngol Head & Neck Surg, Tokyo, Japan

[2] Kitasato Univ, Sch Med, Dept Otorhinolaryngol Head & Neck Surg, Sagamihara, Kanagawa, Japan

[3] Tokyo Med Univ, Hachioji Med Ctr, Dept Otolaryngol Head & Neck Surg, Tokyo, Japan

[4] Int Univ Hlth & Welf Mita Hosp, Dept Head & Neck Oncol & Surg, Tokyo, Japan

[5] Natl Canc Ctr, Dept Head & Neck Surg, Tokyo, Japan

来源：

ACTA OTO-LARYNGOLOGICA | 2020年 / 140卷 / 02期

关键词：

Radiotherapy; chemoradiotherapy; salvage total laryngectomy; pharyngocutaneous fistula; pharyngeal interposition graft; pectoralis major myocutaneous flap; ORGAN PRESERVATION THERAPY; PECTORALIS MYOFASCIAL FLAP; MAJOR MUSCLE FLAP; PHARYNGOCUTANEOUS FISTULA; SURGERY; PREVENTION; CHEMOTHERAPY; RADIATION;

D O I：

10.1080/00016489.2019.1699251

中图分类号：

R76 [耳鼻咽喉科学];

学科分类号：

100213 ;

摘要：

Background: Few studies have demonstrated the utility of pharyngeal interposition graft (PIG) applying pectoralis major myocutaneous flap (PMMCF) by comparing pharyngocutaneous fistula (PCF) rates. Objective: The objective of this retrospective study was to clarify the utility of PIG applying PMMCF in reducing post-operative complications due to salvage total laryngectomy (STL). Material and methods: STL was performed in 59 patients with recurrent laryngeal cancer after radiotherapy, comprising 37 non-PMMCF patients and 22 PMMCF patients. The primary endpoint was PCF rate. Comparisons were made between two groups: a group with simple closure not using PMMCF (non-PMMCF group), and the other with PMMCF used in a PIG (PMMCF group). Results: PCF occurred in 15 of the 59 subjects (25.4%), including 13 of the 37 patients in the non-PMMCF group (35.1%) and 2 of the 22 patients in the PMMCF group (9.1%). PCF rate was significantly lower in the PMMCF group than in the non-PMMCF group (p = .033).

引用

页码：170 / 174

页数：5

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