A mathematical model to optimize the available control measures of

被引:3
作者
Baba, Isa Abdullahi [1 ]
Nasidi, Bashir Ahmad [1 ]
Baleanu, Dumitru [2 ,3 ,4 ]
Saadi, Sultan Hamed [5 ]
机构
[1] Bayero Univ Kano, Dept Math Sci, Kano, Nigeria
[2] Cankaya Univ, Dept Math, TR-06530 Ankara, Turkey
[3] Inst Space Sci, Bucharest, Romania
[4] China Med Univ Hosp, Dept Med Res, Taichung, Taiwan
[5] Near East Univ, Dept Math, Nicosia, Cyprus
关键词
Covid-19; Optimal control; Pontryaging Maximum Principle (PMP); Mathematical model; Existence of control; Stability analysis; EPIDEMICS; DYNAMICS; WUHAN;
D O I
10.1016/j.ecocom.2021.100930
中图分类号
Q14 [生态学(生物生态学)];
学科分类号
071012 ; 0713 ;
摘要
In the absence of valid medicine or vaccine for treating the pandemic Coronavirus (COVID-19) infection, other control strategies like; quarantine, social distancing, self- isolation, sanitation and use of personal protective equipment are effective tool used to prevent and curtail the spread of the disease. In this paper, we present a mathematical model to study the dynamics of COVID-19. We then formulate an optimal control problem with the aim to study the most effective control strategies to prevent the proliferation of the disease. The existence of an optimal control function is established and the Pontryagin maximum principle is applied for the characterization of the controller. The equilibrium solutions (DFE & endemic) are found to be locally asymptotically stable and subsequently the basic reproduction number is obtained. Numerical simulations are carried out to support the analytic results and to explicitly show the significance of the control. It is shown that Quarantine/isolating those infected with the disease is the best control measure at the moment.
引用
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页数:10
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