The Importance of Surgical Margins in Renal Cell and Urothelial Carcinomas

被引:6
作者
Alemozaffar, Mehrdad [1 ]
Filson, Christopher P. [1 ,2 ]
Master, Viraj A. [1 ]
机构
[1] Emory Univ, Dept Urol, 1365 Clifton Rd,Clin B,5th Floor, Atlanta, GA 30322 USA
[2] Atlanta Vet Affairs Med Ctr, Decatur, GA USA
关键词
renal cell carcinoma; urothelial carcinoma; positive surgical margins; nephron-sparing surgery; radical cystectomy; NEPHRON-SPARING SURGERY; LAPAROSCOPIC PARTIAL NEPHRECTOMY; FROZEN-SECTION ANALYSIS; 2ND TRANSURETHRAL RESECTION; PROSTATIC URETHRAL BIOPSY; RADICAL CYSTECTOMY; BLADDER-CANCER; CLINICAL-SIGNIFICANCE; EVALUATING PATIENTS; ONCOLOGIC OUTCOMES;
D O I
10.1002/jso.24121
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
This chapter reviews the prevalence, outcomes, and management of positive surgical margins for patients with either renal cell or urothelial carcinomas. Though renal cell carcinoma tends to be resistant to conventional radio-or chemotherapy, kidney cancer patients with positive surgical margins can often be managed with close surveillance with acceptable outcomes. On the other hand, urothelial tumors tend to be more aggressive, and positive surgical margins after radical cystectomy often requires adjuvant therapy. (c) 2016 Wiley Periodicals, Inc.
引用
收藏
页码:316 / 322
页数:7
相关论文
共 95 条
[1]   Positive vascular wall margins have minimal impact on cancer outcomes in patients with non-metastatic renal cell carcinoma (RCC) with tumour thrombus [J].
Abel, E. Jason ;
Carrasco, Alonso ;
Karam, Jose ;
Tamboli, Pheroze ;
Delacroix, Scott ;
Vaporciyan, Ara A. ;
Wood, Christopher G. .
BJU INTERNATIONAL, 2014, 114 (05) :667-673
[2]   Robotic Versus Laparoscopic Partial Nephrectomy: A Systematic Review and Meta-Analysis [J].
Aboumarzouk, Omar M. ;
Stein, Robert J. ;
Eyraud, Remi ;
Haber, Georges-Pascal ;
Chlosta, Piotr L. ;
Somani, Bhaskar K. ;
Kaouk, Jihad H. .
EUROPEAN UROLOGY, 2012, 62 (06) :1023-1033
[3]   Laparoscopic partial nephrectomy: Evaluation of long-term oncological outcome [J].
Allaf, ME ;
Bhayani, SB ;
Rogers, C ;
Varkarakis, I ;
Link, RE ;
Inagaki, T ;
Jarrett, TW ;
Kavoussi, LR .
JOURNAL OF UROLOGY, 2004, 172 (03) :871-873
[4]   The method of bladder cuff excision during laparoscopic radical nephroureterectomy does not affect oncologic outcomes in upper tract urothelial carcinoma [J].
Allard, Christopher B. ;
Alamri, Abdulaziz ;
Dason, Shawn ;
Farrokhyar, Farough ;
Matsumoto, Edward D. ;
Kapoor, Anil .
WORLD JOURNAL OF UROLOGY, 2013, 31 (01) :175-181
[5]   Prevalence and impact on survival of positive surgical margins in partial nephrectomy for renal cell carcinoma: a population-based study [J].
Ani, Ifeanyi ;
Finelli, Antonio ;
Alibhai, Shabbir M. H. ;
Timilshina, Narhari ;
Fleshner, Neil ;
Abouassaly, Robert .
BJU INTERNATIONAL, 2013, 111 (08) :E300-E305
[6]   EAU Guidelines on Non-Muscle-invasive Urothelial Carcinoma of the Bladder: Update 2013 [J].
Babjuk, Marko ;
Burger, Maximilian ;
Zigeuner, Richard ;
Shariat, Shahrokh F. ;
van Rhijn, Bas W. G. ;
Comperat, Eva ;
Sylvester, Richard J. ;
Kaasinen, Eero ;
Boehle, Andreas ;
Palou Redorta, Joan ;
Roupret, Morgan .
EUROPEAN UROLOGY, 2013, 64 (04) :639-653
[7]   EFFICACY OF 2-CM SURGICAL MARGINS FOR INTERMEDIATE-THICKNESS MELANOMAS (1 TO 4 MM) - RESULTS OF A MULTIINSTITUTIONAL RANDOMIZED SURGICAL TRIAL [J].
BALCH, CM ;
URIST, MM ;
KARAKOUSIS, CP ;
SMITH, TJ ;
TEMPLE, WJ ;
DRZEWIECKI, K ;
JEWELL, WR ;
BARTOLUCCI, AA ;
MIHM, MC ;
BARNHILL, R ;
WANEBO, HJ .
ANNALS OF SURGERY, 1993, 218 (03) :262-269
[8]   Bladder Cancer Patterns of Pelvic Failure: Implications for Adjuvant Radiation Therapy [J].
Baumann, Brian C. ;
Guzzo, Thomas J. ;
He, Jiwei ;
Vaughn, David J. ;
Keefe, Stephen M. ;
Vapiwala, Neha ;
Deville, Curtiland ;
Bekelman, Justin E. ;
Tucker, Kai ;
Hwang, Wei-Ting ;
Malkowicz, S. Bruce ;
Christodouleas, John P. .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2013, 85 (02) :363-369
[9]   Survival benefit of adjuvant radiotherapy in stage III and IV bladder cancer: results of 170 patients [J].
Bayoumi, Yasser ;
Heikal, Tarek ;
Darweish, Hossam .
CANCER MANAGEMENT AND RESEARCH, 2014, 6 :459-465
[10]   Positive Surgical Margin Appears to Have Negligible Impact on Survival of Renal Cell Carcinomas Treated by Nephron-Sparing Surgery [J].
Bensalah, Karim ;
Pantuck, Allan J. ;
Rioux-Leclercq, Nathalie ;
Thuret, Rodolphe ;
Montorsi, Francesco ;
Karakiewicz, Pierre I. ;
Mottet, Nicolas ;
Zini, Laurent ;
Bertini, Roberto ;
Salomon, Laurent ;
Villers, Arnaud ;
Soulie, Michel ;
Bellec, Laurent ;
Rischmann, Pascal ;
De La Taille, Alexandre ;
Avakian, Raffi ;
Crepel, Maxime ;
Ferriere, Jean-Marie ;
Bernhard, Jean-Christophe ;
Dujardin, Thierry ;
Pouliot, Frederic ;
Rigaud, Jerome ;
Pfister, Christian ;
Albouy, Baptiste ;
Guy, Laurent ;
Joniau, Steven ;
van Poppel, Hendrik ;
Lebret, Thierry ;
Culty, Thibault ;
Saint, Fabien ;
Zisman, Amnon ;
Raz, Orit ;
Lang, Herve ;
Spie, Romain ;
Wille, Andreas ;
Roigas, Jan ;
Aguilera, Alfredo ;
Rambeaud, Bastien ;
Martinez Pineiro, Luis ;
Nativ, Ofer ;
Farfara, Roy ;
Richard, Francois ;
Roupret, Morgan ;
Doehn, Christian ;
Bastian, Patrick J. ;
Muller, Stefan C. ;
Tostain, Jacques ;
Belldegrun, Arie S. ;
Patard, Jean-Jacques .
EUROPEAN UROLOGY, 2010, 57 (03) :466-471