A new triterpene glycoside from sea cucumber Holothuria leucospilota

被引:23
作者
Han, Hua [1 ]
Yi, Yang Hua [1 ]
Li, Ling [1 ]
Wang, Xiao Hua [1 ]
Liu, Bao Shu [1 ]
Sun, Peng [1 ]
Pan, Min Xiang [1 ]
机构
[1] Second Mil Med Univ, Sch Pharm, Res Ctr Marine Drugs, Shanghai 200433, Peoples R China
关键词
sea cucumber; Holothuria leucospilota; triterpene glycoside; leucospilotaside A;
D O I
10.1016/j.cclet.2006.12.027
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A new triterpene glycoside, leucospilotaside A, along with a known saponin, isolated from sea cucumber Holothuria leucospilota, and its structure was elucidated as 3 beta-O-[4-O-sodiumsulfate-beta-D-quinovopyranosyl-(1 -> 2)-beta-D-xylopyranosyl]-holosta-22-ketone-9-en-17 alpha,25 alpha-diol (1) by extensive spectroscopic analysis and chemical methods. Leucospilotaside A (1) has a ketone carbonyl group (22) in the aglycon side chain. (c) 2007 Yang Hua YL Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.
引用
收藏
页码:161 / 164
页数:4
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