Chemical Composition and Toxicity of Essential Oils of Piper spp. Against Larvae of Aedes aegypti L. (Diptera: Culicidae)

被引:0
作者
da Costa, Jose G. M. [1 ]
dos Santos, Paula F. [1 ]
Brito, Samara A. [1 ]
Rodrigues, Fabiola F. G. [1 ]
Coutinho, Henrique D. M. [1 ]
Botelho, Marco A. [1 ]
de Lima, Sidney G. [2 ]
机构
[1] Univ Reg Cariri, Dept Quim Biol, Programa Posgrad Bioprospeccao Mol, Lab Pesquisa Prod Nat, BR-63105000 Crato, CE, Brazil
[2] Univ Fed Piaui, Dept Quim, Minist Petronio Portella, BR-64049550 Teresina, PI, Brazil
来源
LATIN AMERICAN JOURNAL OF PHARMACY | 2010年 / 29卷 / 03期
关键词
Biological activity; Dengue fever; GC/MS; Piperaceae; LARVICIDAL ACTIVITY; ADUNCUM;
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
"Chemical Composition and Toxicity of Essential Oils of Piper spp. Against Larvae of Aedes aegypti L. (Diptera: Culicidae)". Aedes aegypti L. is one of the vectors of dengue fever. In Brazil it has gain much attention in the Public Health sector since this disease has becoming more aggressive in the hemorrhagic form in the population. This study aimed to investigate the effect of Piper aduncum, Piper marginal urn and Piper nigrum essential oils against Aedes aegypti larvae. In an effort to find a natural effective and affordable way to control this endemic disease, the larvicidal activities of essential oils from the plants were analyzed for activity comparison by measurement of their LC50. The essential oils isolated by hydrodistillation were analyzed by GC/MS. The main components identified were: beta-pinene (32.7%) and E-caryophyllene (17.1%) in P. aduncum; isoelemecin (21.7%) and apiole (20.1%) in P. marginatum and E-caryophyllene (24.2%) and caryophyllene oxide (20.1%) in P. nigrum. The results show that Piper marginatum presented the LC50 of 8.29 mu g/mL and these are the first report about the larvicidal activity of P. aduncum. These results suggest that the essential oil of Piper species are promising as larvicide against A. aegypti larvae.
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页码:463 / 467
页数:5
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