Health-Related Quality of Life in Children With Congenital Hyperinsulinism

被引:3
作者
Mannisto, Jonna M. E. [1 ,2 ]
Jaaskelainen, Jarmo [1 ,2 ]
Huopio, Hanna [1 ]
机构
[1] Kuopio Univ Hosp, Dept Pediat, Kuopio, Finland
[2] Univ Eastern Finland, Kuopio, Finland
来源
FRONTIERS IN ENDOCRINOLOGY | 2019年 / 10卷
关键词
hypoglycemia; children and adolescent; KINDL-R (R); persistent hyperinsulinemic hypoglycemia; transient hyperinsulinism; ADOLESCENTS; DIAGNOSIS; GERMANY;
D O I
10.3389/fendo.2019.00670
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background: Quality of life (QoL) has not been studied in patients with congenital hyperinsulinism (CHI). Objectives: To examine whether the health-related quality of life (HRQoL) is worsened in patients with persistent or transient CHI. Methods: We studied HRQoL of 65 children with CHI aged 3-17 years (60% males) recruited from the nationwide CHI registry. The median ages were 9.6 (range 3.5-16.3) and 7.4 (3.1-17.9) years in persistent (P-CHI, n = 33) and transient (T-CHI, n = 32) CHI groups, respectively. HRQoL was examined by generic KINDL-R questionnaire and the scores were compared to the age- and gender-specific reference values. Results: In self-reports of subjects aged 11-17 years and in parent reports of children aged 3-17 years, P-CHI or T-CHI children did not have statistically lower scores in any of the six dimensions (physical well-being, emotional well-being, self-esteem, family, friends, and school) or in total scores compared to the reference values. Conclusions: CHI is not associated with low HRQoL in childhood or adolescence.
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页数:5
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