An expedient sequential one-pot four component synthesis of novel steroidal spiro-pyrrolidine heterocycles in ionic liquid

被引：20

作者：

Gavaskar, D. ^{[1
]}

Babu, A. R. Suresh ^{[2
]}

Raghunathan, R. ^{[1
]}

Dharani, M. ^{[3
]}

Balasubramanian, S. ^{[3
]}

机构：

[1] Univ Madras, Dept Organ Chem, Guindy Campus, Madras, Tamil Nadu, India

[2] Univ Strasbourg, IBMC, Strasbourg, France

[3] Univ Madras, Dept Inorgan Chem, Guindy Campus, Madras, Tamil Nadu, India

来源：

STEROIDS | 2016年 / 109卷

关键词：

Estrone; Ionic liquid; Azomethine ylide; Cycloaddition; Indenoquinoxaline; Steroidal pyrrolidine; MEDIATED 3+2 CYCLOADDITION; BIOLOGICAL-ACTIVITY; MULTICOMPONENT REACTIONS; AZOMETHINE YLIDES; DERIVATIVES; FACILE; ANTIBACTERIAL; ESTRONE; LIPS; CONSTRUCTION;

D O I：

10.1016/j.steroids.2016.02.010

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A facile one-pot synthesis of novel steroidal dispiro-indenoquinoxaline pyrrolidines via multicomponent-[3+2]-cycloaddition of azomethine ylides in ionic liquid is described. The structure of cycloadduct is confirmed by IR, H-1 NMR, C-13 NMR, high resolution mass spectroscopy and elemental analysis. (C) 2016 Elsevier Inc. All rights reserved.

引用

页码：1 / 6

页数：6

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