An expedient sequential one-pot four component synthesis of novel steroidal spiro-pyrrolidine heterocycles in ionic liquid

被引：20

作者：

Gavaskar, D. ^{[1
]}

Babu, A. R. Suresh ^{[2
]}

Raghunathan, R. ^{[1
]}

Dharani, M. ^{[3
]}

Balasubramanian, S. ^{[3
]}

机构：

[1] Univ Madras, Dept Organ Chem, Guindy Campus, Madras, Tamil Nadu, India

[2] Univ Strasbourg, IBMC, Strasbourg, France

[3] Univ Madras, Dept Inorgan Chem, Guindy Campus, Madras, Tamil Nadu, India

来源：

STEROIDS | 2016年 / 109卷

关键词：

Estrone; Ionic liquid; Azomethine ylide; Cycloaddition; Indenoquinoxaline; Steroidal pyrrolidine; MEDIATED 3+2 CYCLOADDITION; BIOLOGICAL-ACTIVITY; MULTICOMPONENT REACTIONS; AZOMETHINE YLIDES; DERIVATIVES; FACILE; ANTIBACTERIAL; ESTRONE; LIPS; CONSTRUCTION;

D O I：

10.1016/j.steroids.2016.02.010

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A facile one-pot synthesis of novel steroidal dispiro-indenoquinoxaline pyrrolidines via multicomponent-[3+2]-cycloaddition of azomethine ylides in ionic liquid is described. The structure of cycloadduct is confirmed by IR, H-1 NMR, C-13 NMR, high resolution mass spectroscopy and elemental analysis. (C) 2016 Elsevier Inc. All rights reserved.

引用

页码：1 / 6

页数：6

共 50 条

[11] An expedient one-pot sequential three-component reaction for the stereoselective synthesis of functionalized spiro-sulfamidate imine fused δ-lactone scaffold
Majee, Debashis
Biswas, Soumen
Mobin, Shaikh M.
Samanta, Sampak
TETRAHEDRON LETTERS, 2014, 55 (33) : 4553 - 4558
[12] An expedient, one-pot, stepwise sequential approach for the regioselective synthesis of pyrazolines
Ganesan, Suresh
Sarangapani, Muniraj
Doble, Mukesh
JOURNAL OF CHEMICAL RESEARCH, 2021, 45 (3-4) : 326 - 333
[13] Four-component one-pot synthesis of novel dicyanoaniline-anchored triazoles
Mojtahedi, Mohammad M.
Azhari, Saeede
Abaee, M. Saeed
CANADIAN JOURNAL OF CHEMISTRY, 2022, : 561 - 567
[14] Efficient One-Pot Three-Component Synthesis of Fused Pyridine Derivatives in Ionic Liquid
Huang, Zhibin
Hu, Yu
Zhou, Yao
Shi, Daqing
ACS COMBINATORIAL SCIENCE, 2011, 13 (01) : 45 - 49
[15] A facile four component one-pot synthesis of polyhydroquinoline derivatives catalyzed by ionic liquid via modified Hantzsch reaction
Nirmal, Jay P.
Dadhaniya, Pratish V.
Patel, Manish P.
Patel, Ranjan G.
INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 2010, 49 (05): : 587 - 592
[16] An Unexpected Diastereoselective Synthesis of Novel Substituted Pyridines via One-Pot, Four-Component Reaction
Zangouei, Mahdieh
Esmaeili, Abbas Ali
Mague, Joel T.
SYNLETT, 2016, 27 (11) : 1669 - 1673
[17] One-pot four component synthesis of novel 3-furyl coumarin derivatives
Jalli, Venkata Prasad
Krishnamurthy, Suvratha
Moriguchi, Tetsuji
Tsuge, Akihiko
JOURNAL OF CHEMICAL SCIENCES, 2016, 128 (02) : 217 - 226
[18] A Remarkable One-Pot Sequential Four-Component Synthesis of Tetrahydroquinazolines via an Isocyanide-Based Multicomponent Reaction
Shaabani, Ahmad
Mahyari, Mojtaba
Aghaei, Morteza
Keshipour, Sajjad
Ng, Seik Weng
SYNLETT, 2013, 24 (15) : 1968 - 1972
[19] Facile one-pot synthesis of novel ortho-aminocarbonitriles and dicyanoanilines fused to heterocycles via pseudo four-component reactions
Mojtahedi, Mohammad M.
Pourabdi, Ladan
Abaee, M. Saeed
Jami, Hamed
Dini, Masoud
Halvagar, Mohammad R.
TETRAHEDRON, 2016, 72 (13) : 1699 - 1705
[20] Iodine catalyzed one-pot four component synthesis of coumarinyl phosphoramidates via sequential addition of reactants
Imrankhan, Mohammed
Shivashankar, Kalegowda
NEW JOURNAL OF CHEMISTRY, 2020, 44 (43) : 18573 - 18578

← 1 2 3 4 5 →