A non-enzyme cascade amplification strategy for colorimetric assay of disease biomarkers

被引:26
作者
Li, Jiuxing [1 ]
Gao, Zhuangqiang [1 ,2 ]
Ye, Haihang [1 ]
Wan, Shulin [1 ]
Pierce, Meghan [3 ]
Tang, Dianping [2 ]
Xia, Xiaohu [1 ]
机构
[1] Michigan Technol Univ, Dept Chem, Houghton, MI 49931 USA
[2] Fuzhou Univ, Dept Chem, Collaborat Innovat Ctr Detect Technol Haixi Food, Key Lab Anal & Detect Food Safety,Fujian Prov & M, Fuzhou 350108, Fujian, Peoples R China
[3] Michigan Technol Univ, Dept Chem Engn, Houghton, MI 49931 USA
基金
美国国家科学基金会;
关键词
ENHANCED RAMAN-SCATTERING; PEROXIDASE-LIKE ACTIVITY; ULTRASENSITIVE DETECTION; SIGNAL AMPLIFICATION; GOLD NANOPARTICLES; DNA; IMMUNOASSAY; ELISA; PROTEIN; CANCER;
D O I
10.1039/c7cc04521b
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A non-enzyme cascade amplification strategy, based on the dissolution of Ag nanoparticles and a Pt nanocube-catalyzed reaction, for colorimetric assay of disease biomarkers was developed. This strategy overcomes the intrinsic limitations of enzymes involved in conventional enzymatic amplification techniques, thanks to the utilization of noble-metal nanostructures with superior properties.
引用
收藏
页码:9055 / 9058
页数:4
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