Diagnostic potency of EUS-guided FNA for the evaluation of pancreatic mass lesions

被引:36
作者
Alizadeh, Amir Houshang Mohammad [1 ]
Shahrokh, Shabnam [1 ]
Hadizadeh, Mohammad [1 ]
Padashi, Maryam [1 ]
Zali, Mohammad Reza [1 ]
机构
[1] Shahid Beheshti Univ Med Sci, Res Inst Gastroenterol & Liver Dis, Res Ctr Gastroenterol & Liver Dis, Tehran, Iran
关键词
Diagnosis; endoscopic ultrasound-guided fine-needle aspiration; pancreatic neoplasms; FINE-NEEDLE-ASPIRATION; SINGLE-CENTER EXPERIENCE; ENDOSCOPIC ULTRASOUND; BIOPSY; CANCER; CT; ACCURACY; ULTRASONOGRAPHY; CARCINOMA; CYTOLOGY;
D O I
10.4103/2303-9027.175879
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Background and Objectives: Diagnosis of pancreatic lesions remains a clinical challenge. This study aimed to evaluate the diagnostic accuracy of endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) in pancreatic mass lesions. Patients and Methods: Clinical data, laboratory tests, and cytopathological and imaging reports were collected from 185 pancreatic EUS cases performed from March 2010 to January 2014. The final diagnosis was based on surgical findings, EUS-FNA or computed tomography (CT)-guided biopsy. Results: A total of 100 pancreatic FNAs were obtained by EUS. Most positive diagnoses of malignancy were pancreatic adenocarcinomas (n = 61). The site of pancreatic adenocarcinoma was the head in 50 (82.0%), body in seven (11.5%), and tail in four (6.5%). The sensitivity, specificity, and positive and negative predictive values of EUS-FNA for diagnosing adenocarcinoma were 80.3%, 92.3%, 94.2%, and 75.0%, respectively. Discussion: We concluded that EUS-FNA of pancreatic lesion accurately diagnoses pancreatic adenocarcinoma and should be considered for the standard management of pancreatic adenocarcinoma.
引用
收藏
页码:30 / 34
页数:5
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