Plant metabolomics: large-scale phytochemistry in the functional genomics era

被引：742
作者：
Sumner, LW
Mendes, P
Dixon, RA
机构：
[1] Samuel Roberts Noble Fdn Inc, Div Plant Biol, Ardmore, OK 73401 USA
[2] Virginia Polytech Inst & State Univ, Virginia Bioinformat Inst, Blacksburg, VA 24061 USA
来源：
PHYTOCHEMISTRY | 2003年 / 62卷 / 06期
关键词：
metabolomics; metabolic profiling; metabolite profiling; analytical instrumentation; mass spectrometry; MS; bioinformatics; metabolite; databases; Medicago truncatula;
D O I：
10.1016/S0031-9422(02)00708-2
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Metabolomics or the large-scale phytochemical analysis of plants is reviewed in relation to functional genomics and systems biology. A historical account of the introduction and evolution of metabolite profiling into today's modern comprehensive metabolomics approach is provided. Many of the technologies used in metabolomics, including optical spectroscopy, nuclear magnetic resonance, and mass spectrometry are surveyed. The critical role of bioinformatics and various methods of data visualization are summarized and the future role of metabolomics in plant science assessed. (C) 2003 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：817 / 836
页数：20
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