Currently college students have more and more spare time, and work-study activities becomes a hot topic in their lives. But with the development of college work-study, the current situation is not as optimistic as we have expected. During the process of work-study, the key factor is, on the one hand, how to get the deserved rewards, and on the other hand, how to guarantee their good grades and help their employments and entrepreneurship. On analyzing the current situation of work-study activities, this paper combines the thought of the author and discusses the study of entrepreneurship education in college work-study in details.