Ynol Ethers: Synthesis and Reactivity

被引：4
作者：
Verrier, Charlie [1 ]
Carret, Sebastien [1 ]
Poisson, Jean-Francois [1 ]
机构：
[1] Univ Grenoble Alpes, Dept Chim Mol SERCO, UMR 5250, CNRS,IMCG FR 2607, F-38041 Grenoble, France
来源：
CHIMIA | 2016年 / 70卷 / 1-2期
关键词：
Alkynes; Enol ethers; Ketenes; Synthesis; Ynol ethers; ACETYLENIC ETHERS; ALKYNYL ETHERS; INTRAMOLECULAR CARBOLITHIATION; ASYMMETRIC-SYNTHESIS; EFFICIENT SYNTHESIS; 2+2 CYCLOADDITION; CHEMISTRY; CARBANIONS; REAGENTS; STRATEGY;
D O I：
10.2533/chimia.2016.93
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Ynol ethers are highly valuable substrates offering a wide range of reactivity. These highly electron rich heterosubstitued alkynes can be of great synthetic potential. In this mini-review, the different methods for the synthesis of ynol ethers are first presented, divided in three main approaches involving a beta-elimination, a carbene rearrangement and a direct oxidation of an alkyne. Their reactivity is then summarized underlying their synthetic utility. This non-exhaustive review aims at presenting the intrinsic reactivity of these compounds, still underexploited in synthesis.
引用
收藏
页码：93 / 96
页数：4
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