Perfusion magnetic resonance imaging of the liver

被引：93

作者：

Thng, Choon Hua ^{[2
]}

Koh, Tong San ^{[2
]}

Collins, David J. ^{[1
,3
]}

Koh, Dow Mu ^{[1
]}

机构：

[1] Royal Marsden NHS Fdn Trust, Dept Radiol, Sutton SM2 5PT, Surrey, England

[2] Natl Canc Ctr, Dept Oncol Imaging, Singapore 169610, Singapore

[3] CR UK EPSRC Canc Imaging Ctr, Inst Canc Res, Sutton SM2 5PT, Surrey, England

来源：

WORLD JOURNAL OF GASTROENTEROLOGY | 2010年 / 16卷 / 13期

基金：

英国工程与自然科学研究理事会;

关键词：

Magnetic resonance imaging; Dynamic contrast-enhanced magnetic resonance imaging; Liver; Tracer kinetic modeling; ADVANCED HEPATOCELLULAR-CARCINOMA; DYNAMIC COMPUTED-TOMOGRAPHY; CONTRAST-ENHANCED CT; HEPATIC PERFUSION; COLORECTAL-CANCER; INITIAL-EXPERIENCE; METASTATIC LIVER; BLOOD-FLOW; MODEL; MRI;

D O I：

10.3748/wjg.v16.i13.1598

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Perfusion magnetic resonance imaging (MRI) studies quantify the microcirculatory status of liver parenchyma and liver lesions, and can be used for the detection of liver metastases, assessing the effectiveness of anti-angiogenic therapy, evaluating tumor viability after anticancer therapy or ablation, and diagnosis of liver cirrhosis and its severity. In this review, we discuss the basic concepts of perfusion MRI using tracer kinetic modeling, the common kinetic models applied for analyses, the MR scanning techniques, methods of data processing, and evidence that supports its use from published clinical and research studies. Technical standardization and further studies will help to establish and validate perfusion MRI as a clinical imaging modality. (C) 2010 Baishideng. All rights reserved.

引用

页码：1598 / 1609

页数：12

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