Systemic lupus erythematosus When to consider and management options

被引:0
作者
Apostolopoulos, Diane [1 ]
Hoi, Alberta Yik-Bun [2 ]
机构
[1] Monash Hlth, Dept Rheumatol, Melbourne, Vic, Australia
[2] Monash Med Ctr, Dept Rheumatol, Melbourne, Vic, Australia
关键词
lupus erythematosus; systemic; discoid; EPIDEMIOLOGY; CLASSIFICATION; PREVALENCE; NEPHRITIS; DIAGNOSIS; PATTERNS; CRITERIA; DISEASE;
D O I
暂无
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Background Systemic lupus erythematosus (SLE) is a chronic systemic autoimmune disease that sometimes poses a diagnostic challenge, owing to the wide variety of clinical and immunological presentations. There can be a significant delay between onset of symptoms and the diagnosis of SLE. Appreciation of its typical presentations and diagnostic process can help general practitioners decide on the timing of specialist referral. Objective This article describes clinical and immunological manifestations that are required in the diagnosis of SLE, and provides an overview of management options. Discussion Some of the more common clinical and immunological manifestations of SLE are discussed and case studies to highlight the importance of accurate diagnosis are presented. Control of disease activity is crucial in alleviating symptoms, prevention of damage accrual and early mortality.
引用
收藏
页码:696 / 700
页数:5
相关论文
共 29 条
  • [1] BORGTER EJ, 1990, ARTHRITIS RHEUM, V33, P634
  • [2] SYSTEMIC LUPUS-ERYTHEMATOSUS - CLINICAL AND IMMUNOLOGICAL PATTERNS OF DISEASE EXPRESSION IN A COHORT OF 1,000 PATIENTS
    CERVERA, R
    KHAMASHTA, MA
    FONT, J
    SEBASTIANI, GD
    GIL, A
    LAVILLA, P
    DOMENECH, I
    AYDINTUG, AO
    JEDRYKAGORAL, A
    DERAMON, E
    GALEAZZI, M
    HAGA, HJ
    MATHIEU, A
    HOUSSIAU, F
    INGELMO, M
    HUGHES, GRV
    CERVERA, R
    SEBASTIANI, GD
    FONT, J
    KHAMASHTA, MA
    HUGHES, GRV
    FONT, J
    CERVERA, R
    LOPEZSOTO, A
    VIVANCOS, J
    INGELMO, M
    URBANOMARQUEZ, A
    KHAMASHTA, MA
    VIANNA, J
    HUGHES, GRV
    GIL, A
    LAVILLA, P
    PINTADO, V
    LOPEZDUPLA, M
    VAZQUEZ, JJ
    SEBASTIANI, GD
    DERAMON, E
    CAMPS, M
    FRUTOS, MA
    PERELLO, I
    SANTOS, PG
    ABARCA, M
    NEBRO, AF
    DOMENECH, I
    TOKGOZ, G
    AYDINTUG, AO
    JEDRYKAGORAL, A
    MALDYKOWA, H
    CHWALINSKASADOWSKA, H
    GALEAZZI, M
    [J]. MEDICINE, 1993, 72 (02) : 113 - 124
  • [3] Prevalence of adult systemic lupus erythematosus in California and Pennsylvania in 2000: estimates obtained using hospitalization data
    Chakravarty, Eliza F.
    Bush, Thomas M.
    Manzi, Susan
    Clarke, Ann E.
    Ward, Michael M.
    [J]. ARTHRITIS AND RHEUMATISM, 2007, 56 (06): : 2092 - 2094
  • [4] Asian ethnicity in systemic lupus erythematosus: an Australian perspective
    Connelly, K.
    Morand, E. F.
    Hoi, A. Y.
    [J]. INTERNAL MEDICINE JOURNAL, 2013, 43 (06) : 618 - 624
  • [5] CRONIN ME, 1988, RHEUM DIS CLIN N AM, V14, P99
  • [6] Epidemiology and sociodemographics of systemic lupus erythematosus and lupus nephritis among US adults with Medicaid coverage, 20002004
    Feldman, Candace H.
    Hiraki, Linda T.
    Liu, Jun
    Fischer, Michael A.
    Solomon, Daniel H.
    Alarcon, Graciela S.
    Winkelmayer, Wolfgang C.
    Costenbader, Karen H.
    [J]. ARTHRITIS AND RHEUMATISM, 2013, 65 (03): : 753 - 763
  • [7] FESSLER BJ, 1995, RHEUM DIS CLIN N AM, V21, P81
  • [8] Epidemiology of connective tissue disorders
    Gaubitz, M.
    [J]. RHEUMATOLOGY, 2006, 45 : 3 - 4
  • [9] SYSTEMIC LUPUS-ERYTHEMATOSUS (SLE) - DIFFERENT PREVALENCES IN DIFFERENT POPULATIONS OF AUSTRALIAN ABORIGINALS
    GRENNAN, DM
    BOSSINGHAM, D
    [J]. AUSTRALIAN AND NEW ZEALAND JOURNAL OF MEDICINE, 1995, 25 (02): : 182 - 183
  • [10] Lupus arthritis
    Grossman, Jennifer M.
    [J]. BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY, 2009, 23 (04): : 495 - 506