Ionic liquids vs. microporous solids as reusable reaction media for the catalytic C-H functionalization of indoles with alcohols

被引：25

作者：

Cirujano, Francisco G. ^{[1
]}

Stalpaert, Maxime ^{[1
]}

De Vos, Dirk E. ^{[1
]}

机构：

[1] Univ Leuven, KU Leuven, Dept Microbial & Mol Syst, Ctr Surface Chem & Catalysis,Leuven Chem&Tech, Celestijnenlaan 200F,Post Box 2461, B-3001 Heverlee, Belgium

来源：

GREEN CHEMISTRY | 2018年 / 20卷 / 11期

基金：

欧盟地平线“2020”;

关键词：

FRIEDEL-CRAFTS ALKYLATION; METAL-ORGANIC FRAMEWORKS; PERFORMANCE; MOFS; BEHAVIOR; PATHWAY; ACIDS; FE;

D O I：

10.1039/c8gc00738a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

High performance reusable catalysts and reaction media are evaluated for the green alkylation of indoles with alcohols under mild and solvent-free conditions. For a range of Bronsted and Lewis acid catalytic sites in different environments, such as inexpensive ionic liquids or microporous solids, we show a correlation between the acid strength and catalytic activity, achieving the highest turnovers reported for strong acid sites upon five reuses under mild conditions.

引用

页码：2481 / 2485

页数：5

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