Clinical findings, laboratory data and outcome in dogs with spontaneous hyperadrenocorticism in Croatia

被引：0

作者：

Kis, Ivana ^{[1
]}

Brkljacic, Mirna ^{[1
]}

Torti, Marin ^{[1
]}

Mayer, Iva ^{[1
]}

Smit, Iva ^{[1
]}

Gotic, Jelena ^{[1
]}

Vnuk, Drazen ^{[2
]}

Gusak, Valentina ^{[2
]}

Turkovic, Veljko ^{[3
]}

Matijatko, Vesna ^{[1
]}

机构：

[1] Univ Zagreb, Fac Vet Med, Clin Internal Dis, Heinzelova 55, Zagreb 10000, Croatia

[2] Univ Zagreb, Fac Vet Med, Clin Surg Orthopaed & Ophtalmol, Zagreb 10000, Croatia

[3] Vet Small Anim Clin Hofheim, Hofheim, Germany

来源：

VETERINARSKI ARHIV | 2016年 / 86卷 / 01期

关键词：

canine adrenal gland; diagnostic procedures; outcome; ADRENAL-GLAND TUMORS; PITUITARY-DEPENDENT HYPERADRENOCORTICISM; TRILOSTANE TREATMENT; ULTRASONOGRAPHY; MANAGEMENT; DIAGNOSIS; SURVIVAL; MITOTANE; ACTH;

D O I：

暂无

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

Hyperadrenocorticism (HAC) is one of the most common endocrine disorders in dogs, and establishing a diagnosis requires extensive diagnostics. In this study, 54 dogs with spontaneous hyperadrenocorticism were included, and were divided in two groups: the treated group which consisted of 35 dogs (trilostane therapy 32, adrenalectomy 3) and the non-treated group, which consisted of 19 dogs. According to the Kaplan-Meyer survival curve, the mean survival time of the whole population was 29.6 months, where the untreated patients' mean survival time was 12.7 months, and in patients with therapeutic intervention it was 34.7 months. In the multivariable Cox proportional hazards model, no single clinical or laboratory parameter was found to significantly influence the outcome. The significance of this research is in its contribution to understanding the natural course of spontaneous canine hyperadrenocorticism.

引用

页码：77 / 94

页数：18

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