Nickel-catalyzed Reactions between Enone and Two Ethylenes

被引：11

作者：

Ogoshi, Sensuke ^{[1
]}

Nishimura, Akira ^{[1
]}

Haba, Toshifumi ^{[1
]}

Ohashi, Masato ^{[1
]}

机构：

[1] Osaka Univ, Fac Engn, Dept Appl Chem, Suita, Osaka 5650871, Japan

来源：

CHEMISTRY LETTERS | 2009年 / 38卷 / 12期

关键词：

OXIDATIVE CYCLIZATION; CONJUGATE ADDITION; KEY INTERMEDIATE; CYCLOADDITIONS; ETA(2)-ALKENE; ALDEHYDE; ALKYNES; KETONE; SYSTEM;

D O I：

10.1246/cl.2009.1166

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In the presence of a catalytic amount of Ni(cod)(2) and PCy3, the reaction of (E)-1-phenylbut-2-en-l-one (1a) with ethylene occurred to give three-component addition products, 1,6-enone 2a and 1,5-diketone 4a. The reaction of an enone with two ethylenes gave 2a. The reaction of two enones with an ethylene gave 4a. On the other hand, 2-methyl-1-phenylprop-2-en-1-one (1b) reacted with two ethylenes selectively to give a mixture of 2b and 3b. The reaction might proceed via oxidative cyclization of an enone and an ethylene with nickel(0).

引用

页码：1166 / 1167

页数：2

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