Next generation sequencing of the NOTCH3 gene in a cohort of pulmonary hypertension patients

被引:5
作者
Gomez, Juan [1 ]
Reguero, Julian R. [2 ]
Junquera, Manuel R. [2 ]
Alvarez, Celso [3 ]
Moris, Cesar [2 ,4 ]
Alonso, Belen [1 ]
Iglesias, Sara [1 ]
Coto, Eliecer [1 ,4 ]
机构
[1] Hosp Univ Cent Asturias, Genet Mol Lab Med, Oviedo 33011, Spain
[2] Hosp Univ Cent Asturias, Cardiol Fdn Asturcor, Oviedo 33011, Spain
[3] Hosp Univ Cent Asturias, Neumol, Oviedo 33011, Spain
[4] Univ Oviedo, Dept Med, Oviedo, Spain
关键词
Pulmonary hypertension; NOTCH3; gene; Next generation sequencing; Gene mutation; ARTERIAL-HYPERTENSION;
D O I
10.1016/j.ijcard.2016.02.024
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
[No abstract available]
引用
收藏
页码:149 / 150
页数:2
相关论文
共 10 条
  • [1] The Genetics of Pulmonary Arterial Hypertension
    Austin, Eric D.
    Loyd, James E.
    [J]. CIRCULATION RESEARCH, 2014, 115 (01) : 189 - 202
  • [2] Mutations of NOTCH3 in childhood pulmonary arterial hypertension
    Chida, Ayako
    Shintani, Masaki
    Matsushita, Yoshihisa
    Sato, Hiroki
    Eitoku, Takahiro
    Nakayama, Tomotaka
    Furutani, Yoshiyuki
    Hayama, Emiko
    Kawamura, Yoichi
    Inai, Kei
    Ohtsuki, Shinichi
    Saji, Tsutomu
    Nonoyama, Shigeaki
    Nakanishi, Toshio
    [J]. MOLECULAR GENETICS & GENOMIC MEDICINE, 2014, 2 (03): : 229 - 239
  • [3] A Semiconductor Chip-Based Next Generation Sequencing Procedure for the Main Pulmonary Hypertension Genes
    Gomez, Juan
    Reguero, Julian R.
    Alvarez, Celso
    Junquera, Manuel R.
    Arango, Ana
    Moris, Cesar
    Coto, Eliecer
    [J]. LUNG, 2015, 193 (04) : 571 - 574
  • [4] Mutation Analysis of the Main Hypertrophic Cardiomyopathy Genes Using Multiplex Amplification and Semiconductor Next-Generation Sequencing
    Gomez, Juan
    Reguero, Julian R.
    Moris, Cesar
    Martin, Maria
    Alvarez, Victoria
    Alonso, Belen
    Iglesias, Sara
    Coto, Eliecer
    [J]. CIRCULATION JOURNAL, 2014, 78 (12) : 2963 - U230
  • [5] Definitions and Diagnosis of Pulmonary Hypertension
    Hoeper, Marius M.
    Bogaard, Harm Jan
    Condliffe, Robin
    Frantz, Robert
    Khanna, Dinesh
    Kurzyna, Marcin
    Langleben, David
    Manes, Alessandra
    Satoh, Toru
    Torres, Fernando
    Wilkins, Martin R.
    Badesch, David B.
    [J]. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2013, 62 (25) : D42 - D50
  • [6] The pathogenesis of CADASIL: an update
    Kalaria, RN
    Viitanen, M
    Kalimo, H
    Dichgans, M
    Tabira, T
    [J]. JOURNAL OF THE NEUROLOGICAL SCIENCES, 2004, 226 (1-2) : 35 - 39
  • [7] Notch3 signaling promotes the development of pulmonary arterial hypertension
    Li, Xiaodong
    Zhang, Xiaoxue
    Leathers, Robin
    Makino, Ayako
    Huang, Chengqun
    Parsa, Pouria
    Macias, Jesus
    Yuan, Jason X-J
    Jamieson, Stuart W.
    Thistlethwaite, Patricia A.
    [J]. NATURE MEDICINE, 2009, 15 (11) : 1289 - U89
  • [8] Current pathophysiological concepts and management of pulmonary hypertension
    Lourenco, Andre P.
    Fontoura, Dulce
    Henriques-Coelho, Tiago
    Leite-Moreira, Adelino F.
    [J]. INTERNATIONAL JOURNAL OF CARDIOLOGY, 2012, 155 (03) : 350 - 361
  • [9] Genetics and Genomics of Pulmonary Arterial Hypertension
    Soubrier, Florent
    Chung, Wendy K.
    Machado, Rajiv
    Gruenig, Ekkehard
    Aldred, Micheala
    Geraci, Mark
    Loyd, James E.
    Elliott, C. Gregory
    Trembath, Richard C.
    Newman, John H.
    Humbert, Marc
    [J]. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2013, 62 (25) : D13 - D21
  • [10] Notch Signaling in Pulmonary Hypertension
    Thistlethwaite, Patricia A.
    Li, Xiaodong
    Zhang, Xiaoxue
    [J]. MEMBRANE RECEPTORS, CHANNELS AND TRANSPORTERS IN PULMONARY CIRCULATION, 2010, 661 : 279 - 298