Study of rhinocerebral zygomycosis in an only partially compliant patient

被引:0
作者
Gruber, I. [1 ]
Lackinger, B. [2 ]
机构
[1] Landesklinikum Wiener Neustadt, Abt Augenheilkunde & Optometrie, A-2700 Wiener Neustadt, Austria
[2] Landesklinikum St Polten, Abt Augenheilkunde & Orbitachirurg, St Polten, Austria
关键词
Zygomycosis; mucormycosis; rhinocerebral; compliance; cavernous sinus thrombosis; ocular invasion; FUNGAL-INFECTIONS; MUCORMYCOSIS; POSACONAZOLE; PATHOGENESIS; MANAGEMENT;
D O I
10.1007/s00717-010-0400-3
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
BACKGROUND: Short description of the pathogenicity of zygomycetes. PATIENT AND METHODS: The patient was observed both clinically and by MRI over a period of two years, starting with the first presentation. RESULTS: Description of the applied and rejected diagnostic and therapeutic options and their results. CONCLUSION: In spite of repeated interruptions of treatment the patient was able to maintain a subjective high quality of life over a period of two years. Visual acuity of the right eye amounts to 1.0 s.c., the left eye became blind one week after the first presentation.
引用
收藏
页码:162 / 165
页数:4
相关论文
共 15 条
[1]  
BROWN J, 2005, AM J HLTH SYSTE 1221
[2]   Posaconazole as salvage therapy for zygomycosis [J].
Greenberg, RN ;
Mullane, K ;
van Burik, JAH ;
Raad, I ;
Abzug, MJ ;
Anstead, G ;
Herbrecht, R ;
Langston, A ;
Marr, KA ;
Schiller, G ;
Schuster, M ;
Wingard, JR ;
Gonzalez, CE ;
Revankar, SG ;
Corcoran, G ;
Kryscio, RJ ;
Hare, R .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2006, 50 (01) :126-133
[3]   The iron chelator deferasirox protects mice from mucormycosis through iron starvation [J].
Ibrahim, Ashraf S. ;
Gebermariam, Teclegiorgis ;
Fu, Yue ;
Lin, Lin ;
Husseiny, Mohamed I. ;
French, Samuel W. ;
Schwartz, Julie ;
Skory, Christopher D. ;
Edwards, John E., Jr. ;
Spellbergl, Brad J. .
JOURNAL OF CLINICAL INVESTIGATION, 2007, 117 (09) :2649-2657
[4]   Iron acquisition: a novel perspective on mucormycosis pathogenesis and treatment [J].
Ibrahim, Ashraf S. ;
Spellberg, Brad ;
Edwards, John, Jr. .
CURRENT OPINION IN INFECTIOUS DISEASES, 2008, 21 (06) :620-625
[5]   Predictors of mortality in rhinocerebral mycosis [J].
Jayalakshmi, Sita S. ;
Reddy, Ramana G. ;
Borgohain, Rupam ;
Subramanyam, C. ;
Panigrahi, Manas ;
Sundaram, C. ;
Meena, A. K. ;
Mohandas, S. .
NEUROLOGY INDIA, 2007, 55 (03) :292-297
[6]   Development of Effective Ocular Preparations of Antifungal Agents [J].
Kaur, Indu Pal ;
Rana, Cheena ;
Singh, Harinder .
JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS, 2008, 24 (05) :481-493
[7]   Invasive zygomycosis: Update on pathogenesis, clinical manifestations, and management [J].
Kontoyiannis, Dimitrios P. ;
Lewis, Russell E. .
INFECTIOUS DISEASE CLINICS OF NORTH AMERICA, 2006, 20 (03) :581-+
[8]  
Lai Chih-Cheng, 2008, Journal of Infection and Chemotherapy, V14, P77, DOI 10.1007/s10156-007-0595-7
[9]   Current options in antifungal pharmacotherapy [J].
Mohr, John ;
Johnson, Melissa ;
Cooper, Travis ;
Lewis, James S. ;
Ostrosky-Zeichner, Luis .
PHARMACOTHERAPY, 2008, 28 (05) :614-645
[10]  
Pak Jane, 2008, J Emerg Trauma Shock, V1, P106, DOI 10.4103/0974-2700.42203