Factors in the Breast Core Needle Biopsies of Atypical Ductal Hyperplasia that Can Predict Carcinoma in the Subsequent Surgical Excision Specimens

被引:1
作者
Koo, Ja Seung
Kim, Min Jung [2 ]
Kim, Eun-kyung [2 ]
Jung, Woohee [1 ]
机构
[1] Yonsei Univ, Dept Pathol, Gangnam Severance Hosp, Coll Med, Seoul 135720, South Korea
[2] Yonsei Univ, Dept Diagnost Radiol, Coll Med, Seoul 135720, South Korea
关键词
Breast hyperplasia; Needle biopsy; Risk factor; TERM FOLLOW-UP; IN-SITU; FIBROBLASTIC STROMAGENESIS; LESIONS; CANCER; CLASSIFICATION; DIAGNOSIS;
D O I
10.4048/jbc.2010.13.2.132
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Purpose: Our purpose was to identify the factors in a breast core needle biopsy (CNB) of atypical ductal hyperplasia (ADH) that are predictive for carcinoma in the subsequent excision specimens. Methods: We performed a retrospective pathologic review of 50 cases that were diagnosed as ADH via the CNB and that had the corresponding excision specimens. Results: The size of the largest ADH foci in the CNBs was 0.8 +/- 0.6 mm (mean SD) for benign proliferative disease (BPD, n=12), 1.0 +/- 0.5 mm (mean +/- SD) for ADH (n=9) and 1.3 +/- 0.8 nnm (mean +/- SD) for malignant lesions (n=29) in excision specimens (p=0.105). Among the 30 cases showing stromal alterations around the ducts with ADH in the CNBs, 9 cases (30.0%) were BPD or ADH and 21 cases (70.0%) were malignant lesions in the excision specimens (p=0.004). Conclusion: As the stromal alterations around the ADH were noted in the CNB, there was an increased likelihood that more advanced lesions would be identified in the surgical excision specimens.
引用
收藏
页码:132 / 137
页数:6
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