Emergence of Porcine Circovirus 2 Associated Reproductive Failure in Southern India

被引：24

作者：

Karuppannan, A. K. ^{[1
,2
]}

Ramesh, A. ^{[2
]}

Reddy, Y. K. ^{[2
]}

Ramesh, S. ^{[3
]}

Mahaprabhu, R. ^{[1
]}

Jaisree, S. ^{[1
]}

Roy, P. ^{[1
]}

Sridhar, R. ^{[4
]}

Pazhanivel, N. ^{[4
]}

Sakthivelan, S. M. ^{[4
]}

Sreekumar, C. ^{[5
]}

Murugan, M. ^{[5
]}

Jaishankar, S. ^{[5
]}

Gopi, H. ^{[5
]}

Purushothaman, V. ^{[6
]}

Kumanan, K. ^{[7
]}

Babu, M. ^{[7
]}

机构：

[1] Tamil Nadu Vet & Anim Sci Univ, Centralized Univ Lab, Madras, Tamil Nadu, India

[2] Tamil Nadu Vet & Anim Sci Univ, Vaccine Res Ctr Viral Vaccines, Madras, Tamil Nadu, India

[3] Tamil Nadu Vet & Anim Sci Univ, Cent Instrumentat Lab, Madras Vet Coll, Madras, Tamil Nadu, India

[4] Tamil Nadu Vet & Anim Sci Univ, Dept Pathol, Madras Vet Coll, Madras, Tamil Nadu, India

[5] Tamil Nadu Vet & Anim Sci Univ, Post Grad Res Inst Anim Sci, Madras, Tamil Nadu, India

[6] Tamil Nadu Vet & Anim Sci Univ, Ctr Anim Hlth Studies, Madras, Tamil Nadu, India

[7] Tamil Nadu Vet & Anim Sci Univ, Ctr Anim Prod Studies, Madras, Tamil Nadu, India

来源：

TRANSBOUNDARY AND EMERGING DISEASES | 2016年 / 63卷 / 03期

关键词：

PCV2; reproductive failure; stillbirth; weak piglets; MULTISYSTEMIC WASTING SYNDROME; TYPE-2; PIGS; VIRUSES; DISEASE; SWINE; PCV2;

D O I：

10.1111/tbed.12276

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Incidence of unusually high numbers of stillbirths was observed at a piggery unit at the Veterinary University research farm in Tamil Nadu State of India. Systematic examination of the tissue from stillborn piglets led to the identification of presence of Porcine circovirus 2 (PCV2). Detailed analysis utilizing electron microscopy, polymerase chain reaction and sequencing confirmed the presence of PCV2 in the tissue of affected piglets. Histopathology analysis of the affected piglet tissue showed lymphoid cell depletion of lymphnodes, spleen and infiltration of liver, kidney, myocardium, etc. Retrospective examination of the morbidity and mortality history in the farm revealed high mortality in young and weanling piglets suggestive of PCV2 infection-induced diseases. This is the first report of emergence of major disease incidence in farmed swine due to PCV2 infection in India.

引用

页码：314 / 320

页数：7

共 15 条

[1] Isolation of porcine circovirus-like viruses from pigs with a wasting disease in the USA and Europe [J].

Allan, GM ;

McNeilly, F ;

Kennedy, S ;

Daft, B ;

Clarke, EG ;

Ellis, JA ;

Haines, DM ;

Meehan, BM ;

Adair, BM .

JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION, 1998, 10 (01) :3-10

[2] Pathogenesis of postweaning multisystemic wasting syndrome caused by Porcine circovirus 2:: an immune riddle [J].

Darwich, L ;

Segalés, J ;

Mateu, E .

ARCHIVES OF VIROLOGY, 2004, 149 (05) :857-874

[3] Epidemiologic assessment of porcine circovirus type 2 coinfection with other pathogens in swine [J].

Dorr, Paul M. ;

Baker, Rodney B. ;

Almond, Glen W. ;

Wayne, Spencer R. ;

Gebreyes, Wondwossen A. .

JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 2007, 230 (02) :244-250

[4]

Farnham MW, 2003, CAN J VET RES, V67, P108

[5]

Harding JCS, 1998, SWINE HEALTH PROD, V6, P249

[6] Apoptosis and proliferative activity in lymph node reaction in postweaning multisystemic wasting syndrome (PMWS) [J].

Mandrioli, L ;

Sarli, G ;

Panarese, S ;

Baldoni, S ;

Marcato, PS .

VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 2004, 97 (1-2) :25-37

[7] Spread like a wildfire-The omnipresence of porcine circovirus type 2 (PCV2) and its ever-expanding association with diseases in pigs [J].

Meng, Xiang-Jin .

VIRUS RESEARCH, 2012, 164 (1-2) :1-3

[8] Cardiovascular lesions in pigs naturally or experimentally infected with porcine circovirus type 2 [J].

Opriessnig, T ;

Janke, BH ;

Halbur, PG .

JOURNAL OF COMPARATIVE PATHOLOGY, 2006, 134 (01) :105-110

[9] Influence of long-term vaccination of a breeding herd of pigs against PCV2 on reproductive parameters [J].

Pejsak, Z. ;

Kusior, G. ;

Pomorska-Mol, M. ;

Podgorska, K. .

POLISH JOURNAL OF VETERINARY SCIENCES, 2012, 15 (01) :37-42

[10] Viremia and effect of fetal infection with porcine viruses with special reference to porcine circovirus 2 infection [J].

Pensaert, MB ;

Sanchez, RE ;

Ladekjær-Mikkelsen, AS ;

Allan, GM ;

Nauwynck, HJ .

VETERINARY MICROBIOLOGY, 2004, 98 (02) :175-183

← 1 2 →