Win odds: An adaptation of the win ratio to include ties

被引：47

作者：

Brunner, Edgar ^{[1
]}

Vandemeulebroecke, Marc ^{[2
]}

Muetze, Tobias ^{[3
]}

机构：

[1] Univ Med Ctr Gottingen, Dept Med Stat, Gottingen, Germany

[2] Novartis Pharma AG, Clin Dev & Analyt, Basel, Switzerland

[3] Novartis Pharma AG, Stat Methodol, Novartis Campus, CH-4056 Basel, Switzerland

来源：

STATISTICS IN MEDICINE | 2021年 / 40卷 / 14期

关键词：

multiple sclerosis; nonparametrics; win odds; win ratio;

D O I：

10.1002/sim.8967

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The win ratio, a recently proposed measure for comparing the benefit of two treatment groups, allows ties in the data but ignores ties in the inference. In this article, we highlight some difficulties that this can lead to, and we propose to focus on the win odds instead, a modification of the win ratio which takes ties into account. We construct hypothesis tests and confidence intervals for the win odds, and we investigate their properties through simulations and in a case study. We conclude that the win odds should be preferred over the win ratio.

引用

页码：3367 / 3384

页数：18

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