Proposal of a genetic classifier for risk group stratification in pediatric T-cell lymphoblastic lymphoma reveals differences from adult T-cell lymphoblastic leukemia

被引：42

作者：

Balbach, S. T. ^{[1
]}

Makarova, O. ^{[1
]}

Bonn, B. R. ^{[1
]}

Zimmermann, M. ^{[2
]}

Oschlies, I. ^{[3
,4
,5
]}

Klapper, W. ^{[3
,4
,5
]}

Roessig, C. ^{[1
]}

Burkhardt, B. ^{[1
]}

机构：

[1] Univ Childrens Hosp, Pediat Hematol & Oncol, Munster, Germany

[2] Hannover Med Sch, Pediat Hematol & Oncol, Hannover, Germany

[3] Univ Kiel, Hematopathol Sect, Pathol, Campus Kiel, Kiel, Germany

[4] Univ Kiel, Lymph Node Registry, Campus Kiel, Kiel, Germany

[5] Univ Hosp Schleswig Holstein, Campus Kiel, Kiel, Germany

来源：

LEUKEMIA | 2016年 / 30卷 / 04期

关键词：

CHILDHOOD; CHILDREN; ADOLESCENTS; RELAPSE; PTEN;

D O I：

10.1038/leu.2015.203

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：970 / 973

页数：5

共 15 条

[1] NOTCH1 activation clinically antagonizes the unfavorable effect of PTEN inactivation in BFM-treated children with precursor T-cell acute lymphoblastic leukemia [J].

Bandapalli, Obul R. ;

Zimmermann, Martin ;

Kox, Corinne ;

Stanulla, Martin ;

Schrappe, Martin ;

Ludwig, Wolf-Dieter ;

Koehler, Rolf ;

Muckenthaler, Martina U. ;

Kulozik, Andreas E. .

HAEMATOLOGICA, 2013, 98 (06) :928-936

[2] The impact of PTEN regulation by CK2 on PI3K-dependent signaling and leukemia cell survival [J].

Barata, Joao T. .

ADVANCES IN ENZYME REGULATION, VOL 51, 2011, 51 :37-49

[3] Whole exome sequencing hints at a unique mutational profile of paediatric T-cell lymphoblastic lymphoma [J].

Bonn, Bettina R. ;

Huge, Andreas ;

Rohde, Marius ;

Oschlies, Ilske ;

Klapper, Wolfram ;

Voss, Reinhard ;

Makarova, Olga ;

Rossig, Claudia ;

Juergens, Heribert ;

Seggewiss, Jochen ;

Burkhardt, Birgit .

BRITISH JOURNAL OF HAEMATOLOGY, 2015, 168 (02) :308-313

[4] Incidence and prognostic relevance of genetic variations in T-cell lymphoblastic lymphoma in childhood and adolescence [J].

Bonn, Bettina R. ;

Rohde, Marius ;

Zimmermann, Martin ;

Krieger, David ;

Oschlies, Ilske ;

Niggli, Felix ;

Wrobel, Grazyna ;

Attarbaschi, Andishe ;

Escherich, Gabriele ;

Klapper, Wolfram ;

Reiter, Alfred ;

Burkhardt, Birgit .

BLOOD, 2013, 121 (16) :3153-3160

[5] Loss of heterozygosity on chromosome 6q14-q24 is associated with poor outcome in children and adolescents with T-cell lymphoblastic lymphoma [J].

Burkhardt, B. ;

Bruch, J. ;

Zimmermann, M. ;

Strauch, K. ;

Parwaresch, R. ;

Ludwig, W-D ;

Harder, L. ;

Schlegelberger, B. ;

Mueller, F. ;

Harbott, J. ;

Reiter, A. .

LEUKEMIA, 2006, 20 (08) :1422-1429

[6]

Burkhardt B, 2009, HEMATOLOGY M REPORTS, V3, P87

[7] Poor Outcome for Children and Adolescents With Progressive Disease or Relapse of Lymphoblastic Lymphoma: A Report From the Berlin-Frankfurt-Muenster Group [J].

Burkhardt, Birgit ;

Reiter, Alfred ;

Landmann, Eva ;

Lang, Peter ;

Lassay, Lisa ;

Dickerhoff, Roswitha ;

Lakomek, Max ;

Henze, Guenter ;

von Stackelberg, Arend .

JOURNAL OF CLINICAL ONCOLOGY, 2009, 27 (20) :3363-3369

[8] Clinical Impact of NOTCH1 and/or FBXW7 Mutations, FLASH Deletion, and TCR Status in Pediatric T-Cell Lymphoblastic Lymphoma [J].

Callens, Celine ;

Baleydier, Frederic ;

Lengline, Etienne ;

Ben Abdelali, Raouf ;

Petit, Arnaud ;

Villarese, Patrick ;

Cieslak, Agata ;

Minard-Colin, Veronique ;

Rullier, Anne ;

Moreau, Anne ;

Baruchel, Andre ;

Schmitt, Claudine ;

Asnafi, Vahid ;

Bertrand, Yves ;

Macintyre, Elizabeth .

JOURNAL OF CLINICAL ONCOLOGY, 2012, 30 (16) :1966-1973

[9] The role of the PTEN/AKT pathway in NOTCH1-induced leukemia [J].

Palomero, Teresa ;

Dominguez, Maria ;

Ferrando, Adolfo A. .

CELL CYCLE, 2008, 7 (08) :965-970

[10] RAS oncogene mutations and outcome of therapy for childhood acute lymphoblastic leukemia [J].

Perentesis, JP ;

Bhatia, S ;

Boyle, E ;

Shao, Y ;

Shu, XO ;

Steinbuch, M ;

Sather, HN ;

Gaynon, P ;

Kiffmeyer, W ;

Envall-Fox, J ;

Robinson, LL .

LEUKEMIA, 2004, 18 (04) :685-692

← 1 2 →